Global Patent Index - EP 1064380 A1

EP 1064380 A1 2001-01-03 - EXPRESSION OF THE $i(INSL4) GENE IN HUMAN EMBRYONIC BONE TISSUES AND APPLICATIONS

Title (en)

EXPRESSION OF THE $i(INSL4) GENE IN HUMAN EMBRYONIC BONE TISSUES AND APPLICATIONS

Title (de)

EXPRESSION DES INSL4-GENS IN HUMANEM EMBRYONALEM KNOCHENGEWEBE UND IHRE VERWENDUNG

Title (fr)

EXPRESSION DU GENE $i(INSL4) DANS LES TISSUS OSSEUX EMBRYONNAIRES HUMAINS ET APPLICATIONS

Publication

EP 1064380 A1 (FR)

Application

EP 99900993 A

Priority

  • FR 9900137 W
  • FR 9800715 A

Abstract (en)

[origin: FR2774095A1] An INSL4 gene characterized in that it is expressed in human embryonic bone tissue and ligaments, is new. Independent claims are also included for the following: (1) EPIL 1, 2 and 3 encoded by INSL4; (2) a method to detect or identify the localization and/or level of a specific EPIL 1, 2 or 3, or INSL4, or their homologues or variants in a biological sample of bone tissue or ligaments, for the diagnosis of a pathology associated with abnormal EPIL 1, 2 or 3 or INSL4; (3) kits for (2); (4) methods to mark cells of bone tissue and/or ligaments; (5) a method of identifying chemical or biochemical compositions capable of modulating differentiation, regeneration and/or proliferation of human and/or animals bone tissue and/or ligament cells; and (6) a chemical or biochemical composition identified by (5).

IPC 1-7 (main, further and additional classification)

C12N 15/16; A61K 38/28; A61K 39/395; C07H 21/00; C07K 14/64; C07K 16/26; C12N 5/10; C12P 21/02; C12Q 1/68; G01N 33/569; G01N 33/68

IPC 8 full level (invention and additional information)

G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 19/00 (2006.01); C07H 21/00 (2006.01); C07K 14/64 (2006.01); C07K 16/26 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/16 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)

CPC (invention and additional information)

G01N 33/74 (2013.01); C07K 14/64 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9937780A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

FR 2774095 A1 19990730; FR 2774095 B1 20021213; CA 2319076 A1 19990729; EP 1064380 A1 20010103; JP 2002500888 A 20020115; WO 9937780 A1 19990729

INPADOC legal status


2003-11-05 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030429

2002-01-23 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20011210

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000821

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE