Global Patent Index - EP 1064383 A2

EP 1064383 A2 2001-01-03 - INTERFERON ALPHA PLASMIDS AND DELIVERY SYSTEMS, AND METHODS OF MAKING AND USING THE SAME

Title (en)

INTERFERON ALPHA PLASMIDS AND DELIVERY SYSTEMS, AND METHODS OF MAKING AND USING THE SAME

Title (de)

INTERFERON-ALPHA PLASMIDE UND APPLICATIONSSYSTEME, UND METHODE FÜR IHRE HERSTELLUNG UND IHRE VERWENDUNGEN

Title (fr)

PLASMIDES D'INTERFERON ALPHA, SYSTEMES D'ADMINISTRATION ET PROCEDES DE FABRICATION DESDITS PLASMIDES

Publication

EP 1064383 A2 (EN)

Application

EP 99911340 A

Priority

  • US 9905394 W
  • US 7865498 P

Abstract (en)

[origin: WO9947678A2] The present invention relates to gene delivery and gene therapy, and provides novel nucleic acid constructs for expression of interferon alpha in a mammal, formulations for delivery that incorporate a nucleic acid construct for expression, and methods for preparing and using such constructs and formulations. In particular, this invention relates to plasmid constructs for delivery of therapeutic interferon alpha encoding nucleic acids to cells in order to modulate tumor activity, methods of using those constructs (including combination therapy with other agents, such as cytokines, preferably IL-12), as well as methods for preparing such constructs.

IPC 1-7 (main, further and additional classification)

C12N 15/21; A61K 48/00; C07K 14/54; C07K 14/56; C12N 5/10; C12N 15/24; C12N 15/85; C12N 15/88

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 9/127 (2006.01); A61K 38/21 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); C07K 14/56 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/21 (2006.01); C12N 15/85 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 14/5434 (2013.01); C07K 14/56 (2013.01); C12N 15/85 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2830/42 (2013.01); C12N 2840/20 (2013.01)

Citation (search report)

See references of WO 9947678A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9947678 A2 19990923; WO 9947678 A3 19991209; WO 9947678 A9 20001109; AU 3000399 A 19991011; CA 2323604 A1 19990923; EP 1064383 A2 20010103; JP 2002506647 A 20020305

INPADOC legal status


2005-06-15 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20041210

2004-09-15 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040730

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000928

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE