Global Patent Index - EP 1066320 A1

EP 1066320 A1 2001-01-10 - ORPHAN NUCLEAR RECEPTOR

Title (en)

ORPHAN NUCLEAR RECEPTOR

Title (de)

ZELLKERN WAISENREZEPTOR

Title (fr)

RECEPTEUR NUCLEAIRE ORPHELIN

Publication

EP 1066320 A1 (EN)

Application

EP 99914221 A

Priority

  • US 9906737 W
  • US 7959398 P

Abstract (en)

[origin: WO9948915A1] The present invention relates to a novel human orphan nuclear receptor that binds to a cytochrome P-450 monooxygenase (CYP) promoter and that is activated by compounds that induce CYP gene expression. The invention further relates to nucleic acid sequences encoding such a receptor, to methods of making the receptor and to methods of using the receptor and nucleic acid sequences encoding same. The invention also relates to non-human animals transformed to express the human receptor and to methods of using such animals to screen compounds for drug interactions and toxicities.

IPC 1-7 (main, further and additional classification)

C07K 14/00; C07K 14/435; C07K 14/705; C12N 5/16; C12N 15/12; C12N 15/62; C12N 15/63; G01N 33/53; G01N 33/566

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C07K 14/705 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/566 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C12Q 1/6897 (2013.01); C07K 14/70567 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9948915 A1 19990930; WO 9948915 A9 19991118; AU 3211699 A 19991018; EP 1066320 A1 20010110; EP 1066320 A4 20050316; JP 2002535241 A 20021022

INPADOC legal status


2005-06-08 [18W] WITHDRAWN

- Effective date: 20050418

2005-03-16 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20050131

2001-01-10 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000925

2001-01-10 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE