Global Patent Index - EP 1066323 A1

EP 1066323 A1 2001-01-10 - TREATMENT AND PREVENTION OF VASCULAR DISEASE

Title (en)

TREATMENT AND PREVENTION OF VASCULAR DISEASE

Title (de)

BEHANDLUNG UND VERHINDERUNG VON VASKULÄREN KRANKHEITEN

Title (fr)

TRAITEMENT ET PREVENTION DES AFFECTIONS VASCULAIRES

Publication

EP 1066323 A1 (EN)

Application

EP 99915041 A

Priority

  • US 9906595 W
  • US 7968198 P

Abstract (en)

[origin: WO9950296A1] The present invention relates to the discovery that a nucleic acid molecule as set forth in SEQ ID NO:1 encodes a polypeptide (SEQ ID NO:2) that mediates the intracellular signal induced by the binding of TGF beta to specific cell surface receptors. In addition, it has been determined that the polypeptide of SEQ ID NO:2 also acts to increase the secretion of TGF beta . Moreover, the polypeptide (SEQ ID NO:4) encoded by the nucleic acid molecule as set forth in SEQ ID NO:3 was determined to modulate the activity of SEQ ID NO:2.

IPC 1-7 (main, further and additional classification)

C07K 14/495; A61K 38/18; C07K 14/81; C12Q 1/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 38/55 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61P 29/00 (2006.01); C07K 14/495 (2006.01); C07K 14/745 (2006.01); C07K 14/81 (2006.01); C12Q 1/00 (2006.01)

CPC (invention and additional information)

C07K 14/495 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9950296A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9950296 A1 19991007; AU 3365299 A 19991018; CA 2324476 A1 19991007; EP 1066323 A1 20010110; HU 0101731 A2 20010928; IL 138692 D0 20011031; JP 2002509711 A 20020402

INPADOC legal status


2004-04-21 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031001

2001-01-10 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000926

2001-01-10 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE