Global Patent Index - EP 1066528 A1

EP 1066528 A1 2001-01-10 - ASSAY FOR GROWTH DIFFERENTIATION FACTOR 9

Title (en)

ASSAY FOR GROWTH DIFFERENTIATION FACTOR 9

Title (de)

VERSUCHSANORDNUNG FÜR DEN WACHSTUMSDIFFERENZIERUNGSFAKTOR 9

Title (fr)

ANALYSE DU FACTEUR 9 DE DIFFERENCIATION DE CROISSANCE

Publication

EP 1066528 A1 (EN)

Application

EP 99915200 A

Priority

  • US 9907210 W
  • US 8038598 P

Abstract (en)

[origin: WO9950672A1] The present invention relates to a method of identifying an agent which alters (inhibits, enhances) activity of GDF-9. The method involves combining cells having a receptor for GDF-9 and a gene, wherein expression of the gene is regulated by binding of GDF-9 to the receptor; GDF-9; and an agent to be assessed. The combination produced is maintained under conditions appropriate for binding of GDF-9 to the receptors on the cells. The extent to which binding of GDF-9 to the receptors on the cells occurs is then determined, wherein binding of GDF-9 to the receptor to a lesser or greater extent in the presence of the agent to be assessed than in its absence, is indicative of an agent which alters GDF-9 activity.

IPC 1-7 (main, further and additional classification)

G01N 33/68; G01N 33/50

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)

CPC (invention and additional information)

G01N 33/689 (2013.01); G01N 33/74 (2013.01); G01N 2333/475 (2013.01); G01N 2500/00 (2013.01)

Citation (search report)

See references of WO 9950672A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Designated extension state (EPC)

AL LT LV MK RO SI

EPO simple patent family

WO 9950672 A1 19991007; AU 3377799 A 19991018; AU 753793 B2 20021031; CA 2325019 A1 19991007; EP 1066528 A1 20010110; JP 2002510055 A 20020402; MX PA00009653 A 20020508; NZ 507484 A 20030630

INPADOC legal status


2010-01-13 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20090723

2004-10-13 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040825

2001-01-10 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001017

2001-01-10 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-01-10 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20001017;LT PAYMENT 20001017;LV PAYMENT 20001017;MK PAYMENT 20001017;RO PAYMENT 20001017;SI PAYMENT 20001017