Global Patent Index - EP 1067960 A2

EP 1067960 A2 2001-01-17 - A METHOD OF INDUCING AN ANTI-TUMOR RESPONSE AGAINST A LUNG METASTASIS IN A MELANOMA PATIENT

Title (en)

A METHOD OF INDUCING AN ANTI-TUMOR RESPONSE AGAINST A LUNG METASTASIS IN A MELANOMA PATIENT

Title (de)

VERFAHREN ZUR INDUZIERUNG EINER ANTI-TUMOR ANTWORT GEGEN LUNGMETASTASE VON EINES MELANOMAPATIENTEN

Title (fr)

PROCEDE D'INDUCTION D'UNE REPONSE ANTI-TUMORALE CONTRE UNE METASTASE CHEZ UN PATIENT SOUFFRANT DE MELANOME

Publication

EP 1067960 A2 (EN)

Application

EP 99916518 A

Priority

  • US 9907725 W
  • US 8125698 P

Abstract (en)

[origin: WO9952546A2] The present invention is directed to a method of inducing an anti-tumor response against a metastatic melanoma by administering an effective amount of a composition comprising at least one of the following: (i) a hapten-modified syngeneic mammalian melanoma cell substantially in a no growth phase, (ii) a hapten-modified melanoma cell membrane, (iii) a peptide isolated from said hapten-modified melanoma cell or membrane and (iv) a T cell capable of mediating an anti-tumor response such as for example regression of a melanoma. The metastatic melanoma treated according to the present invention includes metastatic melanoma which is limited to the lung and is preferably a small lung metastasis. The invention is further directed to a melanoma cell, an isolated melanoma cell membrane, a peptide isolated from such cell or membrane and a T cell having the property of inducing an anti-tumor response, a composition containing such cell, membrane, peptide, T cell or combination thereof, as well as the methods for theirisolation and preparation.

IPC 1-7 (main, further and additional classification)

A61K 39/00; A61K 35/00

IPC 8 full level (invention and additional information)

A61K 31/675 (2006.01); A61K 35/24 (2006.01); A61K 35/28 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01)

CPC (invention and additional information)

A61K 39/0011 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/6012 (2013.01)

Citation (search report)

See references of WO 9952546A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9952546 A2 19991021; WO 9952546 A3 19991216; AR 020067 A1 20020410; AU 3482199 A 19991101; CA 2327339 A1 19991021; CN 1301174 A 20010627; EP 1067960 A2 20010117; JP 2003524583 A 20030819; PL 366240 A1 20050124

INPADOC legal status


2001-08-16 [18W] WITHDRAWN

- Date of withdrawal: 20010618

2001-01-17 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001108

2001-01-17 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE