EP 1067960 A2 20010117 - A METHOD OF INDUCING AN ANTI-TUMOR RESPONSE AGAINST A LUNG METASTASIS IN A MELANOMA PATIENT
Title (en)
A METHOD OF INDUCING AN ANTI-TUMOR RESPONSE AGAINST A LUNG METASTASIS IN A MELANOMA PATIENT
Title (de)
VERFAHREN ZUR INDUZIERUNG EINER ANTI-TUMOR ANTWORT GEGEN LUNGMETASTASE VON EINES MELANOMAPATIENTEN
Title (fr)
PROCEDE D'INDUCTION D'UNE REPONSE ANTI-TUMORALE CONTRE UNE METASTASE CHEZ UN PATIENT SOUFFRANT DE MELANOME
Publication
Application
Priority
- US 9907725 W 19990409
- US 8125698 P 19980409
Abstract (en)
[origin: WO9952546A2] The present invention is directed to a method of inducing an anti-tumor response against a metastatic melanoma by administering an effective amount of a composition comprising at least one of the following: (i) a hapten-modified syngeneic mammalian melanoma cell substantially in a no growth phase, (ii) a hapten-modified melanoma cell membrane, (iii) a peptide isolated from said hapten-modified melanoma cell or membrane and (iv) a T cell capable of mediating an anti-tumor response such as for example regression of a melanoma. The metastatic melanoma treated according to the present invention includes metastatic melanoma which is limited to the lung and is preferably a small lung metastasis. The invention is further directed to a melanoma cell, an isolated melanoma cell membrane, a peptide isolated from such cell or membrane and a T cell having the property of inducing an anti-tumor response, a composition containing such cell, membrane, peptide, T cell or combination thereof, as well as the methods for theirisolation and preparation.
IPC 1-7
IPC 8 full level
A61K 31/675 (2006.01); A61K 35/24 (2006.01); A61K 35/28 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01)
CPC (source: EP US)
A61K 39/00119 (2018.08 - EP US); A61P 35/00 (2018.01 - EP); A61P 35/04 (2018.01 - EP); A61K 2039/5152 (2013.01 - EP); A61K 2039/6012 (2013.01 - EP); A61K 2039/876 (2018.08 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9952546 A2 19991021; WO 9952546 A3 19991216; AR 020067 A1 20020410; AU 3482199 A 19991101; CA 2327339 A1 19991021; CN 1301174 A 20010627; EP 1067960 A2 20010117; JP 2003524583 A 20030819; PL 366240 A1 20050124
DOCDB simple family (application)
US 9907725 W 19990409; AR P990101625 A 19990409; AU 3482199 A 19990409; CA 2327339 A 19990409; CN 99806236 A 19990409; EP 99916518 A 19990409; JP 2000543156 A 19990409; PL 36624099 A 19990409