EP 1068225 A2 20010117 - NEW COMPOUNDS FOR DNA-TRANSFECTION
Title (en)
NEW COMPOUNDS FOR DNA-TRANSFECTION
Title (de)
NEUE VERBINDUNGEN ZUR TRANSFEKTION VON NUKLEINSAEUREN
Title (fr)
NOUVEAUX COMPOSES DESTINES A LA TRANSFECTION D'ADN
Publication
Application
Priority
- EP 99919208 A 19990407
- EP 9902361 W 19990407
- EP 98106302 A 19980407
- EP 98124837 A 19981230
Abstract (en)
[origin: WO9951629A2] The invention relates to conjugates of lipids and basic, modified membrane disturbing peptides, characterized in that the peptides comprises a reversed amide backbone, particularly compounds of formula (I), wherein R<1> and R<2> are a hydrocarbyl moiety of a straight-chain or branched-chain, saturated or unsaturated aliphatic carboxylic acid or a phospholipid moiety, R<3> is a basic, modified membrane disturbing peptide with a reversed amide backbone, Y is C2-10 alkylene, X is -C(O)-NH- or -S-S-, and salts thereof.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C12N 15/09 (2006.01); C12N 15/88 (2006.01)
CPC (source: EP)
C12N 15/88 (2013.01)
Citation (search report)
See references of WO 9951629A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9951629 A2 19991014; WO 9951629 A3 19991223; AU 3706599 A 19991025; CA 2327367 A1 19991014; EP 1068225 A2 20010117; JP 2002510706 A 20020409
DOCDB simple family (application)
EP 9902361 W 19990407; AU 3706599 A 19990407; CA 2327367 A 19990407; EP 99919208 A 19990407; JP 2000542350 A 19990407