Global patent index - EP 1068225 A2

EP 1068225 A2 2001-01-17 - NEW COMPOUNDS FOR DNA-TRANSFECTION

Title (en)

NEW COMPOUNDS FOR DNA-TRANSFECTION

Title (de)

NEUE VERBINDUNGEN ZUR TRANSFEKTION VON NUKLEINSAEUREN

Title (fr)

NOUVEAUX COMPOSES DESTINES A LA TRANSFECTION D'ADN

Publication

EP 1068225 A2 (EN)

Application

EP 99919208 A

Priority

  • EP 99919208 A
  • EP 9902361 W
  • EP 98106302 A
  • EP 98124837 A

Abstract (en)

[origin: WO9951629A2] The invention relates to conjugates of lipids and basic, modified membrane disturbing peptides, characterized in that the peptides comprises a reversed amide backbone, particularly compounds of formula (I), wherein R<1> and R<2> are a hydrocarbyl moiety of a straight-chain or branched-chain, saturated or unsaturated aliphatic carboxylic acid or a phospholipid moiety, R<3> is a basic, modified membrane disturbing peptide with a reversed amide backbone, Y is C2-10 alkylene, X is -C(O)-NH- or -S-S-, and salts thereof.

IPC 1-7 (main, further and additional classification)

C07K 14/00; A61K 9/127; A61K 47/48

IPC 8 full level (invention and additional information)

A61K 9/127 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C12N 15/09 (2006.01); C12N 15/88 (2006.01)

CPC (invention and additional information)

C12N 15/88 (2013.01)

Citation (search report)

See references of WO 9951629A3

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9951629 A2 19991014; WO 9951629 A3 19991223; AU 3706599 A 19991025; CA 2327367 A1 19991014; EP 1068225 A2 20010117; JP 2002510706 A 20020409

INPADOC legal status

2005-07-20 [18R] REFUSED

- Ref Legal Event Code: 18R

- Effective date: 20050129

2004-01-21 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20031208

2001-01-17 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20001107

2001-01-17 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE