Global Patent Index - EP 1068298 A1

EP 1068298 A1 2001-01-17 - $i(IN VITRO) MODEL FOR VIRAL INFECTION AND IMMUNE RESPONSE

Title (en)

$i(IN VITRO) MODEL FOR VIRAL INFECTION AND IMMUNE RESPONSE

Title (de)

IN VITRO MODEL FÜR VIRUSINFEKTION UND IMMUNE ANTWORT

Title (fr)

MODELE $i(IN VITRO) D'INFECTION VIRALE ET REACTION IMMUNITAIRE

Publication

EP 1068298 A1 (EN)

Application

EP 99908581 A

Priority

  • US 9904425 W
  • US 7634898 P

Abstract (en)

[origin: WO9943788A1] An in vitro model system for viral infection and for immune response is comprised of a tissue block from adult tonsil or lymph node supported on a matrix which is flexible and porous and wherein the supported tissue block is cultured in a medium whose surface is congruent with the tissue block/matrix interface. The histoculture system can be used to screen fon antiviral drugs, to monitor the course of viral diseases, and to monitor an immune response to antigen stimulation.

IPC 1-7 (main, further and additional classification)

C12N 5/08; C12N 5/00

IPC 8 full level (invention and additional information)

C12N 5/078 (2010.01); G01N 33/50 (2006.01)

CPC (invention and additional information)

G01N 33/5088 (2013.01); C12N 5/0651 (2013.01); C12N 2533/54 (2013.01); G01N 2333/16 (2013.01); G01N 2333/78 (2013.01); G01N 2500/00 (2013.01)

Citation (search report)

See references of WO 9943788A1

Designated contracting state (EPC)

BE CH DE FR GB LI

EPO simple patent family

WO 9943788 A1 19990902; AU 2797799 A 19990915; EP 1068298 A1 20010117

INPADOC legal status


2011-01-05 [18R] REFUSED

- Effective date: 20100617

2003-10-15 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030902

2001-01-31 [RTI1] TITLE (CORRECTION)

- Free text: IN VITRO MODEL FOR VIRAL INFECTION AND IMMUNE RESPONSE

2001-01-17 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000828

2001-01-17 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): BE CH DE FR GB LI