EP 1068304 A4 20010509 - TREATMENT OF PARASITIC DISEASES BY INHIBITION OF CYSTEINE PROTEASES OF THE PAPAIN SUPERFAMILY
Title (en)
TREATMENT OF PARASITIC DISEASES BY INHIBITION OF CYSTEINE PROTEASES OF THE PAPAIN SUPERFAMILY
Title (de)
BAHANDLUNG PARASITÄRER KRANKHEITEN DURCH HEMMUNG VON CYSTEINPROTEASEN DER PAPAIN-ÜBERFAMILIE
Title (fr)
TRAITEMENT DE MALADIES PARASITAIRES PAR L'INHIBITION DES CYSTEINE-PROTEASES DE LA SUPERFAMILLE DE LA PAPAINE
Publication
Application
Priority
- US 9907723 W 19990408
- US 8122198 P 19980409
Abstract (en)
[origin: WO9953039A1] The present invention relates to compounds and pharmaceutical compositions which inhibit proteases, such as cysteine proteases. In particular, the present invention relates to compounds and pharmaceutical compositions which inhibit cysteine proteases of the papain superfamily. The compounds and pharmaceutical compositions of the present invention are useful for treating diseases, particularly parasitic diseases, which are mediated by such proteases. In particular, the present invention relates to a method of treating malaria by inhibiting the cysteine protease falcipain.
IPC 1-7
C12N 9/99; C12N 9/48; A01N 43/78; A01N 37/18; A01N 33/26; C07D 413/00; C07D 401/00; C07D 277/60; C07C 241/00; C07C 281/06; C07C 311/29
IPC 8 full level
A61K 31/27 (2006.01); A61K 31/341 (2006.01); A61K 31/40 (2006.01); A61K 31/427 (2006.01); A61K 31/4402 (2006.01); A61K 31/4418 (2006.01); A61K 31/4436 (2006.01); A61K 31/4439 (2006.01); A61K 31/501 (2006.01); A61K 31/5375 (2006.01); A61P 33/02 (2006.01); C12N 9/48 (2006.01); A61P 33/06 (2006.01); A61P 33/10 (2006.01); A61P 33/12 (2006.01); C07C 281/06 (2006.01); C07C 311/29 (2006.01); C07D 207/24 (2006.01); C07D 207/273 (2006.01); C07D 213/56 (2006.01); C07D 295/215 (2006.01); C07D 307/22 (2006.01); C07D 307/33 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C12N 9/99 (2006.01); C07D 207/26 (2006.01)
CPC (source: EP KR)
A61P 33/00 (2018.01 - EP); A61P 33/02 (2018.01 - EP); A61P 33/06 (2018.01 - EP); A61P 33/10 (2018.01 - EP); A61P 33/12 (2018.01 - EP); C07C 281/06 (2013.01 - EP); C07C 311/29 (2013.01 - EP); C07D 207/273 (2013.01 - EP); C07D 213/56 (2013.01 - EP); C07D 295/215 (2013.01 - EP); C07D 307/22 (2013.01 - EP); C07D 409/12 (2013.01 - EP); C07D 413/12 (2013.01 - EP); C07D 417/12 (2013.01 - EP); C12N 9/99 (2013.01 - KR); Y02A 50/30 (2018.01 - EP)
Citation (search report)
- [X] WO 9805336 A1 19980212 - SMITHKLINE BEECHAM CORP [US], et al
- [X] WO 9716433 A1 19970509 - SMITHKLINE BEECHAM CORP [US], et al
- See also references of WO 9953039A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9953039 A1 19991021; AR 020065 A1 20020410; AU 3482099 A 19991101; CA 2327282 A1 19991021; CN 1304447 A 20010718; CO 5080800 A1 20010925; DZ 2752 A1 20030915; EP 1068304 A1 20010117; EP 1068304 A4 20010509; HU P0101513 A2 20010828; IL 138628 A0 20011031; JP 2002511491 A 20020416; KR 20010042535 A 20010525; MA 26618 A1 20041220; NO 20005032 D0 20001006; NO 20005032 L 20001116; PE 20000421 A1 20000521; PL 343373 A1 20010813; TR 200002940 T2 20010221
DOCDB simple family (application)
US 9907723 W 19990408; AR P990101578 A 19990407; AU 3482099 A 19990408; CA 2327282 A 19990408; CN 99807012 A 19990408; CO 99020595 A 19990408; DZ 990053 A 19990407; EP 99916517 A 19990408; HU P0101513 A 19990408; IL 13862899 A 19990408; JP 2000543587 A 19990408; KR 20007011178 A 20001007; MA 25522 A 19990405; NO 20005032 A 20001006; PE 00029099 A 19990409; PL 34337399 A 19990408; TR 200002940 T 19990408