EP 1068317 A2 20010117 - HUMAN NUCLEIC ACID SEQUENCES FROM PROSTATE TUMOUR TISSUE
Title (en)
HUMAN NUCLEIC ACID SEQUENCES FROM PROSTATE TUMOUR TISSUE
Title (de)
MENSCHLICHE NUKLEINSÄURESEQUENZEN AUS PROSTATATUMORGEWEBE
Title (fr)
SEQUENCES D'ACIDE NUCLEIQUE HUMAINES ISSUES DE TISSUS TUMORAUX PROSTATIQUES
Publication
Application
Priority
- DE 9900721 W 19990309
- DE 19811193 A 19980310
Abstract (en)
[origin: EP1234879A2] Nucleic acid sequences (A) that are expressed at high level in prostatic tumor tissue and encode gene products or their fragments are new. (A) is: (a) one of 54 sequences (all reproduced), all fully defined in the specification; (b) allelic variants of 38 of these sequences; or (c) the complements of these 38 sequences. Independent claims are also included for the following: (1) bacterial or phage artificial chromosomes, or cosmid clones, containing functional genes and their chromosomal locations corresponding to (A), for use as gene transfer vehicles; (2) fragments of (A) large enough to hybridize to (A); (3) expression cassette (EC) comprising (A), or its fragments, plus at least one control or regulatory element; (4) DNA fragments containing a gene obtained using (A); (5) host cells containing (A) or its fragments as a heterologous component of the genome; (6) recombinant production of polypeptides (I), or their fragments, by culturing these cells; (7) antibodies (Ab) directed against (I) or its fragments; (8) 74 polypeptide partial sequences (I), all reproduced, and sequences at least 80 (especially 90) % homologous with them; (9) a pharmaceutical composition containing at least one (I); and (10) genomic genes, their promoters, enhancers, silencers, exon or intron structures, or slice variants, obtained using (A).
IPC 1-7
C12N 15/12; C07K 14/47; C07K 16/18; C12N 1/21; C12N 5/10; C12N 15/10; C12N 15/62; C12N 15/70; C12N 15/79; C12Q 1/68; G01N 33/68; A61K 38/17; A61K 48/00
IPC 8 full level
G01N 33/68 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 13/02 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01)
CPC (source: EP)
A61P 13/02 (2018.01); A61P 35/00 (2018.01); C07K 14/47 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IT LI NL PT SE
DOCDB simple family (publication)
EP 1234879 A2 20020828; EP 1234879 A3 20021030; EP 1234879 B1 20080702; AT E399862 T1 20080715; DE 19811193 A1 19990916; DE 59914802 D1 20080814; EP 1068317 A2 20010117; JP 2002505877 A 20020226; WO 9946374 A2 19990916; WO 9946374 A3 20000706
DOCDB simple family (application)
EP 02090141 A 19990309; AT 02090141 T 19990309; DE 19811193 A 19980310; DE 59914802 T 19990309; DE 9900721 W 19990309; EP 99917785 A 19990309; JP 2000535741 A 19990309