EP 1070063 A1 20010124 - INDOL-3-YL-CYCLOHEXYL AMINE DERIVATIVES FOR THE TREATMENT OF DEPRESSION (5-HT1 RECEPTOR ANTAGONISTS)
Title (en)
INDOL-3-YL-CYCLOHEXYL AMINE DERIVATIVES FOR THE TREATMENT OF DEPRESSION (5-HT1 RECEPTOR ANTAGONISTS)
Title (de)
INDOL-3-YL-CYCLOHEXYL AMINE DERIVATE ZUR BEHANDLUNG VON DEPRESSIONEN (5-HT1 REZEPTOR ANTAGONISTEN)
Title (fr)
DERIVES D'AMINE INDOL-3-YL-CYCLHEXYLE UTILISES DANS LE TRAITEMENT DE LA DEPRESSION (ANTAGONISTES DU RECEPTEUR 5-HT1)
Publication
Application
Priority
- US 9907606 W 19990407
- US 5724498 A 19980408
Abstract (en)
[origin: WO9951592A1] Compounds effective in treating disorders of the serotonin-affected neurological symptoms (5-HT1A receptor active) are provided, such compounds having formula (I), wherein: R1 and R5 are each, independently, hydrogen, halogen, lower alkoxy, lower alkyl, cyano, or trifluoromethyl; R2 and R4 are each, independently, hydrogen, lower alkyl, phenyl, or substituted phenyl; R3 is hydrogen or lower alkyl; and X and Y are each, independently, O, NR6, or CH2, wherein R6 is hydrogen, lower alkyl, phenyl, or substituted phenyl; or pharmaceutically acceptable salts thereof.
IPC 1-7
IPC 8 full level
A61K 31/404 (2006.01); A61K 31/498 (2006.01); A61K 31/538 (2006.01); A61P 25/24 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01)
CPC (source: EP)
A61P 25/24 (2017.12); C07D 405/12 (2013.01)
Citation (search report)
See references of WO 9951592A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9951592 A1 19991014; AU 3476599 A 19991025; CA 2327360 A1 19991014; CN 1304409 A 20010718; EP 1070063 A1 20010124; JP 2002510682 A 20020409
DOCDB simple family (application)
US 9907606 W 19990407; AU 3476599 A 19990407; CA 2327360 A 19990407; CN 99807010 A 19990407; EP 99916450 A 19990407; JP 2000542313 A 19990407