Global Patent Index - EP 1070125 A2

EP 1070125 A2 2001-01-24 - HUMAN NUCLEIC ACID SEQUENCES FROM NORMAL BREAST TISSUE

Title (en)

HUMAN NUCLEIC ACID SEQUENCES FROM NORMAL BREAST TISSUE

Title (de)

MENCHLICHE NUKLEINSAEUREFRAGMENTE, DEREN EXPRESSION IN BRUSTNORMALGEWEBE ERHOEHT IST

Title (fr)

SEQUENCES D'ACIDES NUCLEIQUES HUMAINS PROVENANT DE TISSUS MAMMAIRES SAINS

Publication

EP 1070125 A2 (DE)

Application

EP 99924684 A

Priority

  • DE 9900909 W
  • DE 19813835 A

Abstract (en)

[origin: DE19813835A1] Human nucleic acid sequences from normal breast tissue are new. A nucleic acid sequence that encodes (part of) a gene product comprises: (a) a nucleic acid sequence (I), chosen from a group of 43 sequences (given in the specification); (b) an allelic variant (II) of (I); or (c) a nucleic acid sequence (III), that is complementary to (I) or (II). Independent claims are also included for: (1) a nucleic acid sequence (76 sequences given in the specification), characterized in that it has increased expression in normal breast tissue; (2) BAC, PAC and cosmid clones, containing functional genes and their chromosomal localization, corresponding to one of 76 sequences for use as vehicles for gene transfer; (3) a nucleic acid sequence comprising part of a sequence as above which is sufficiently large to hybridize to a sequence as above; (4) an expression cassette comprising a nucleic acid fragment or a sequence as above, together with at least a control or regulatory sequence; (5) a DNA fragment, comprising a gene, that is produced as a result of using a nucleic acid sequence as above; (6) a host cell containing genetic information for expression of a heterologous nucleic acid sequence as above; (7) a process to manufacture a polypeptide or fragments, characterized in that the host cell above is cultivated; (8) an antibody against a polypeptide, which is encoded by a nucleic acid as above; (9) a polypeptide partial sequence having one of 122 sequences (given in the specification); (10) a genomic gene, its promoter, enhancer, silencer, exon and intron structure and splice variants, generated from cDNA having one of the 76 sequences; and (11) 1318, 3283 and 538 bp nucleic acid sequences characterized in that they are associated with fat metabolism and can be used to treat illnesses associated with an altered fat metabolism.

IPC 1-7 (main, further and additional classification)

C12N 15/00

IPC 8 full level (invention and additional information)

G01N 33/68 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C07K 14/47 (2013.01)

Citation (search report)

See references of WO 9947655A3

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

EPO simple patent family

DE 19813835 A1 19990923; EP 1070125 A2 20010124; JP 2002506639 A 20020305; WO 9947655 A2 19990923; WO 9947655 A3 20000706

INPADOC legal status


2005-04-13 [18D] DEEMED TO BE WITHDRAWN

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- Effective date: 20041001

2004-05-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: HINZMANN, BERND, DR.

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2004-05-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: ROSENTHAL, ANDRE, PROF.

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2004-05-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: SPECHT, THOMAS, DR.

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2004-05-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: PILARSKY, CHRISTIAN, DR.

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2004-05-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: DAHL, EDGAR, DR.

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2002-02-06 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: METAGEN PHARMACEUTICALS GMBH

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2001-01-24 [17P] REQUEST FOR EXAMINATION FILED

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- Effective date: 20000810

2001-01-24 [AK] DESIGNATED CONTRACTING STATES:

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- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE