EP 1070253 A1 20010124 - USE OF hRORalpha RECEPTORS FOR SCREENING SUBSTANCES USEFUL FOR THE TREATMENT OF ATHEROSCLEROSIS
Title (en)
USE OF hRORalpha RECEPTORS FOR SCREENING SUBSTANCES USEFUL FOR THE TREATMENT OF ATHEROSCLEROSIS
Title (de)
VERWENDUNG VON hRORalpha REZEPTOREN ZUR AUFFINDUNG VON ANTI-ATHEROSCLEROTISCHEN VERBINDUNGEN
Title (fr)
UTILISATION DE RECEPTEURS hRORalpha POUR LE CRIBLAGE DE SUBSTANCES UTILES POUR LE TRAITEMENT DE L'ATHEROSCLEROSE
Publication
Application
Priority
- EP 9902001 W 19990324
- FR 9803475 A 19980320
Abstract (en)
[origin: FR2776388A1] ROR (Retinoic acid receptor related Orphan Receptor) receptors and/or their response elements are used to screen for substances having anti-atherosclerotic activity. An Independent claim is also included for a screening assay for substances having anti-atherosclerotic activity, comprising contacting a test substance with a ROR receptor and/or a ROR receptor response element and measuring the binding of the substance to the receptor or the binding of a complex formed between the substance and the receptor to its response element.
IPC 1-7
IPC 8 full level
G01N 33/50 (2006.01); A61K 45/00 (2006.01); A61P 9/10 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP US)
A61P 9/10 (2018.01 - EP); G01N 33/566 (2013.01 - EP US); G01N 2333/70567 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated extension state (EPC)
LT LV RO SI
DOCDB simple family (publication)
US 6998254 B1 20060214; AT E388399 T1 20080315; AU 3521599 A 19991018; AU 752062 B2 20020905; CA 2326141 A1 19991007; CA 2326141 C 20110426; DE 69938297 D1 20080417; DE 69938297 T2 20090319; DK 1070253 T3 20080623; EP 1070253 A1 20010124; EP 1070253 B1 20080305; ES 2303374 T3 20080801; FR 2776388 A1 19990924; FR 2776388 B1 20060428; JP 2004500539 A 20040108; JP 4520039 B2 20100804; NZ 507761 A 20021025; PT 1070253 E 20080617; WO 9950660 A1 19991007
DOCDB simple family (application)
US 64692400 A 20000925; AT 99916886 T 19990324; AU 3521599 A 19990324; CA 2326141 A 19990324; DE 69938297 T 19990324; DK 99916886 T 19990324; EP 9902001 W 19990324; EP 99916886 A 19990324; ES 99916886 T 19990324; FR 9803475 A 19980320; JP 2000541518 A 19990324; NZ 50776199 A 19990324; PT 99916886 T 19990324