EP 1071669 A1 20010131 - BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT
Title (en)
BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT
Title (de)
BICYCLEN MIT EINER ANTITHROMBOTISCHEN WIRKUNG
Title (fr)
BICYCLENES A EFFET ANTITHROMBOTIQUE
Publication
Application
Priority
- DE 19816983 A 19980417
- EP 9902464 W 19990413
Abstract (en)
[origin: WO9954313A1] The invention relates to novel 6-membered bicyclic compounds of general formula (I) Ra-Het-A-Ar-Rb, wherein Ra, Rb, A, Ar and Het have the meanings given in claim 1, their tautomers, stereoisomers, mixtures and salts and especially their physiologically compatible salts with inorganic or organic acids or bases, with valuable properties. The compounds of general formula (I) above wherein Rb stands for a cyano group represent valuable intermediate products for producing the other compounds of general formula (I) above and the compounds of general formula (I) above wherein Rb represents one of the following amidino groups and their tautomers and stereoisomers have valuable pharmacological properties, especially an anti-thrombitic effect.
IPC 1-7
C07D 239/80; A61K 31/395; C07D 217/24; C07D 239/96; C07D 401/12; C07D 239/91; C07D 403/04; C07D 401/04; C07D 403/12; C07D 403/08; C07D 239/74; C07D 239/78; C07D 471/04; C07D 215/22; C07D 215/38; C07D 401/08
IPC 8 full level
A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/472 (2006.01); A61K 31/4985 (2006.01); A61K 31/517 (2006.01); A61P 7/02 (2006.01); C07D 215/22 (2006.01); C07D 215/227 (2006.01); C07D 215/38 (2006.01); C07D 217/24 (2006.01); C07D 239/74 (2006.01); C07D 239/78 (2006.01); C07D 239/80 (2006.01); C07D 239/91 (2006.01); C07D 239/96 (2006.01); C07D 241/42 (2006.01); C07D 401/04 (2006.01); C07D 401/08 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/08 (2006.01); C07D 403/12 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); C07D 215/227 (2013.01); C07D 215/38 (2013.01); C07D 217/24 (2013.01); C07D 239/74 (2013.01); C07D 239/78 (2013.01); C07D 239/80 (2013.01); C07D 239/91 (2013.01); C07D 239/96 (2013.01); C07D 401/04 (2013.01); C07D 401/08 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/08 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01)
Citation (search report)
See references of WO 9954313A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9954313 A1 19991028; AU 4030399 A 19991108; CA 2323606 A1 19991028; DE 19816983 A1 19991021; EP 1071669 A1 20010131; JP 2002512234 A 20020423
DOCDB simple family (application)
EP 9902464 W 19990413; AU 4030399 A 19990413; CA 2323606 A 19990413; DE 19816983 A 19980417; EP 99923410 A 19990413; JP 2000544652 A 19990413