Global patent index - EP 1071669 A1

EP 1071669 A1 2001-01-31 - BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT

Title (en)

BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT

Title (de)

BICYCLEN MIT EINER ANTITHROMBOTISCHEN WIRKUNG

Title (fr)

BICYCLENES A EFFET ANTITHROMBOTIQUE

Publication

EP 1071669 A1 (DE)

Application

EP 99923410 A

Priority

  • DE 19816983 A
  • EP 9902464 W

Abstract (en)

[origin: WO9954313A1] The invention relates to novel 6-membered bicyclic compounds of general formula (I) Ra-Het-A-Ar-Rb, wherein Ra, Rb, A, Ar and Het have the meanings given in claim 1, their tautomers, stereoisomers, mixtures and salts and especially their physiologically compatible salts with inorganic or organic acids or bases, with valuable properties. The compounds of general formula (I) above wherein Rb stands for a cyano group represent valuable intermediate products for producing the other compounds of general formula (I) above and the compounds of general formula (I) above wherein Rb represents one of the following amidino groups and their tautomers and stereoisomers have valuable pharmacological properties, especially an anti-thrombitic effect.

IPC 1-7 (main, further and additional classification)

C07D 239/80; A61K 31/395; C07D 215/22; C07D 215/38; C07D 217/24; C07D 239/74; C07D 239/78; C07D 239/91; C07D 239/96; C07D 401/04; C07D 401/08; C07D 401/12; C07D 403/04; C07D 403/08; C07D 403/12; C07D 471/04

IPC 8 full level (invention and additional information)

A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/472 (2006.01); A61K 31/4985 (2006.01); A61K 31/517 (2006.01); A61P 7/02 (2006.01); C07D 215/22 (2006.01); C07D 215/227 (2006.01); C07D 215/38 (2006.01); C07D 217/24 (2006.01); C07D 239/74 (2006.01); C07D 239/78 (2006.01); C07D 239/80 (2006.01); C07D 239/91 (2006.01); C07D 239/96 (2006.01); C07D 241/42 (2006.01); C07D 401/04 (2006.01); C07D 401/08 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/08 (2006.01); C07D 403/12 (2006.01); C07D 471/04 (2006.01)

CPC (invention and additional information)

C07D 215/227 (2013.01); C07D 215/38 (2013.01); C07D 217/24 (2013.01); C07D 239/74 (2013.01); C07D 239/78 (2013.01); C07D 239/80 (2013.01); C07D 239/91 (2013.01); C07D 239/96 (2013.01); C07D 401/04 (2013.01); C07D 401/08 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/08 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01)

Citation (search report)

See references of WO 9954313A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9954313 A1 19991028; AU 4030399 A 19991108; CA 2323606 A1 19991028; DE 19816983 A1 19991021; EP 1071669 A1 20010131; JP 2002512234 A 20020423

INPADOC legal status

2003-11-12 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030506

2003-03-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG

- Ref Legal Event Code: RAP1

2002-12-11 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20021025

2001-01-31 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20001117

2001-01-31 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE