Global Patent Index - EP 1071773 A1

EP 1071773 A1 2001-01-31 - SH2 DOMAIN-CONTAINING PEPTIDES

Title (en)

SH2 DOMAIN-CONTAINING PEPTIDES

Title (de)

PEPTIDEN DIE EIN SH2-DOMAIN ENTHALTEN

Title (fr)

PEPTIDES CONTENANT LE DOMAINE SH2

Publication

EP 1071773 A1 (EN)

Application

EP 99919975 A

Priority

  • US 9908847 W
  • US 8276798 P
  • US 11329698 P

Abstract (en)

[origin: WO9954467A1] The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, antagonists and agonists vectors and host cells expressing, and immunoadhesions and antibodies to PRO201, PRO308 or PRO309 polypeptides. The invention further relates to compositions and method for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based in part on the identification of genes that are amplified in the genome of tumor cells. Such gene amplification is expected to be associated with the overexpression of the gene product and contribute to tumorigenesis. Accordingly, the proteins encoded by the amplified genes are believed to be useful targets for the diagnosis and/or treatment (including prevention) of certain tumors (e.g. cancer) and may act as predictors of the prognosis of tumor treatment.

IPC 1-7 (main, further and additional classification)

C12N 15/12; C07K 14/47; G01N 33/53; C12Q 1/68; C12N 15/62; C12N 15/11; C07K 16/18

IPC 8 full level (invention and additional information)

G01N 33/53 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 16/42 (2006.01); C07K 19/00 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

C07K 14/47 (2013.01); C07K 2319/02 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Designated extension state (EPC)

AL LT LV MK RO SI

EPO simple patent family

WO 9954467 A1 19991028; WO 9954467 A9 19991216; AU 3757099 A 19991108; AU 741133 B2 20011122; CA 2324297 A1 19991028; EP 1071773 A1 20010131; JP 2002512032 A 20020423; JP 3659405 B2 20050615

INPADOC legal status


2009-02-04 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20080807

2006-09-27 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040728

2004-09-15 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040728

2001-01-31 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001102

2001-01-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-01-31 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20001102;LT PAYMENT 20001102;LV PAYMENT 20001102;MK PAYMENT 20001102;RO PAYMENT 20001102;SI PAYMENT 20001102