Global Patent Index - EP 1071808 A1

EP 1071808 A1 2001-01-31 - TELOMERASE ASSAY OF BODY FLUIDS FOR CANCER SCREENING AND ASSESSMENT OF DISEASE STAGE AND PROGNOSIS

Title (en)

TELOMERASE ASSAY OF BODY FLUIDS FOR CANCER SCREENING AND ASSESSMENT OF DISEASE STAGE AND PROGNOSIS

Title (de)

TELOMERASETEST VON KÖRPERFLÜSSIGKEITEN ZUM SCREENEN, ZUR FESTSTELLUNG DES KRANKHEITSSTADIUMS UND DER PROGNOSE VON KREBS

Title (fr)

DOSAGE DE TELOMERASE PRELEVE DANS DES LIQUIDES ORGANIQUES UTILISE POUR LE DEPISTAGE DU CANCER, L'EVALUATION DU STADE D'EVOLUTION DE LA MALADIE ET L'ETABLISSEMENT DU PRONOSTIC

Publication

EP 1071808 A1 (EN)

Application

EP 99907069 A

Priority

  • US 9903302 W
  • US 7479398 P

Abstract (en)

[origin: WO9941406A1] Elevated telomerase activity levels in tissue and cell extracts have been used to determine the presence of cancer in a tissue sample. The invention herein is directed to an improved telomeric repeat amplification protocol (TRAP) assay for quantitating telomerase RNA or telomerase activity levels, using easily obtainable body fluids, such as blood, plasma, lymph, pleural fluid, spinal fluid, saliva, sputum, urine, and semen, for example, to both detect the presence of cancer as well as assess the stage of the disease and the prognosis of the patient. The improved TRAP assay can be used as a diagnostic marker for malignancy as well as a means of monitoring the progress and effectiveness of cancer therapies.

IPC 1-7 (main, further and additional classification)

C12Q 1/00; C12P 19/34; C12Q 1/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6886 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01)

Citation (search report)

See references of WO 9941406A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9941406 A1 19990819; AU 2682299 A 19990830; CA 2321259 A1 19990819; EP 1071808 A1 20010131; JP 2002503480 A 20020205

INPADOC legal status


2003-04-02 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020901

2001-01-31 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000912

2001-01-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE