EP 1071959 A2 20010131 - METHOD FOR IDENTIFYING CHEMICAL ACTIVE AGENTS AND ACTIVE AGENTS FOR INHIBITING THE 1-DESOXY-D-XYLULOSE-5-PHOSPHATE BIOSYNTHETIC PATHWAY
Title (en)
METHOD FOR IDENTIFYING CHEMICAL ACTIVE AGENTS AND ACTIVE AGENTS FOR INHIBITING THE 1-DESOXY-D-XYLULOSE-5-PHOSPHATE BIOSYNTHETIC PATHWAY
Title (de)
IDENTIFIZIERUNG CHEMISCHER WIRKSTOFFE ZUR HEMMUNG DES 1-DESOXY-D-XYLULOSE-5-PHOSPHAT-BIOSYNTHESEWEGS IN PARASITEN
Title (fr)
PROCEDE D'IDENTIFICATION DE PRINCIPES ACTIFS CHIMIQUES ET PRINCIPES ACTIFS DESTINES A L'INHIBITION DE LA VOIE DE BIOSYNTHESE DU 1-DESOXY-D-XYLULOSE-5-PHOSPHATE
Publication
Application
Priority
- DE 19816196 A 19980414
- DE 19825585 A 19980609
- DE 19828097 A 19980624
- DE 19831637 A 19980715
- DE 19831639 A 19980715
- DE 19831638 A 19980715
- DE 19843279 A 19980922
- EP 9902463 W 19990413
Abstract (en)
[origin: WO9952938A2] The invention relates to a method for identifying chemical active agents which are suitable for treating infectious diseases caused by single- or multi-celled parasites. According to the method, proteins which form part of the 1-desoxy-d-xylulose-5-phosphate metabolic pathway or derivatives thereof which act in the same way are brought into contact with the active agents being tested for their effectiveness against parasites and those active agents which inhibit the proteins or their derivatives are selected. The invention also relates to the active agents which are identified and to their use for producing medicaments for treating parasitic infections.
[origin: WO9952938A2] The invention relates to a method for identifying chemical active agents which are suitable for treating infectious diseases caused by single- or multi-celled parasites. According to the method, proteins which form part of the 1-desoxy-d-xylulose-5-phosphate metabolic pathway or derivatives thereof which act in the same way are brought into contact with the active agents being tested for their effectiveness against parasites and those active agents which inhibit the proteins or their derivatives are selected. The invention also relates to the active agents which are identified and to their use for producing medicaments for treating parasitic infections.
IPC 1-7
IPC 8 full level
A01N 57/18 (2006.01); A01N 57/20 (2006.01); A01H 5/00 (2006.01); A61K 31/662 (2006.01); A61K 45/00 (2006.01); A61P 33/00 (2006.01); A61P 33/02 (2006.01); A61P 33/06 (2006.01); A61P 33/10 (2006.01); A61P 43/00 (2006.01); C07K 14/00 (2006.01); C07K 14/445 (2006.01); C07K 16/00 (2006.01); C12N 5/10 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 15/09 (2006.01); C12N 15/52 (2006.01); C12P 21/02 (2006.01); C12Q 1/527 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A01N 57/18 (2013.01); A61P 33/00 (2018.01); A61P 33/02 (2018.01); A61P 33/06 (2018.01); A61P 33/10 (2018.01); A61P 43/00 (2018.01); C07K 14/445 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12Q 1/527 (2013.01); G01N 33/6893 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9952938 A2 19991021; WO 9952938 A3 19991209; AP 2000001937 A0 20001231; AU 4481699 A 19991101; AU 753169 B2 20021010; CA 2328157 A1 19991021; CN 1297532 A 20010530; EP 1071959 A2 20010131; HU P0101711 A2 20010928; IL 138721 A0 20011031; JP 2002511486 A 20020416; MX PA00010069 A 20020806; OA 11500 A 20040514; PL 358989 A1 20040823; SK 15232000 A3 20010510; TR 200002972 T2 20010122
DOCDB simple family (application)
EP 9902463 W 19990413; AP 2000001937 A 19990413; AU 4481699 A 19990413; CA 2328157 A 19990413; CN 99805023 A 19990413; EP 99920648 A 19990413; HU P0101711 A 19990413; IL 13872199 A 19990413; JP 2000543494 A 19990413; MX PA00010069 A 19990413; OA 1200000280 A 20001012; PL 35898999 A 19990413; SK 15232000 A 19990413; TR 200002972 T 19990413