EP 1073420 A2 20010207 - SPECIALLY DEVISED NEURONAL IMPLANTS FOR RECONSTRUCTION OF DAMAGED CENTRAL NERVOUS SYSTEM
Title (en)
SPECIALLY DEVISED NEURONAL IMPLANTS FOR RECONSTRUCTION OF DAMAGED CENTRAL NERVOUS SYSTEM
Title (de)
SPEZIELLES NEURONALIMPLANTAT ZUM WIEDERAUFBAU EINES BESCHÄDIGTEN ZENTRALNERVENSYSTEMS
Title (fr)
IMPLANTS NEURONAUX SPECIAUX, POUR LA RECONSTRUCTION DU SYSTEME NERVEUX CENTRAL ENDOMMAGE
Publication
Application
Priority
- IL 9900257 W 19990514
- US 8550298 P 19980514
Abstract (en)
[origin: WO9958042A2] Specially devised neuronal implants for reconstruction of damaged central nervous system are prepared by culturing embryonal or neonatal tissue explants in a suspension culture with biodegradable microcarriers allowing formation of cellular-microcarrier aggregates. The cellular-microcarrier aggregates are transferred to plastic dishes coated with a matrix gel composed of hyaluronic acid and laminin, and the cellular-microcarrier aggregates are cultured in a suitable culture medium, forming a composite implant suitable for transplantation.
IPC 1-7
IPC 8 full level
A61K 35/30 (2015.01); C12N 5/0793 (2010.01)
CPC (source: EP)
A61K 35/30 (2013.01); C12N 5/0619 (2013.01); C12N 2506/08 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE
DOCDB simple family (publication)
WO 9958042 A2 19991118; WO 9958042 A3 20000406; AU 3728099 A 19991129; EP 1073420 A2 20010207; EP 1073420 A4 20040908
DOCDB simple family (application)
IL 9900257 W 19990514; AU 3728099 A 19990514; EP 99919517 A 19990514