EP 1073458 A4 20050112 - CHLAMYDIA PROTEINS AND THEIR USES
Title (en)
CHLAMYDIA PROTEINS AND THEIR USES
Title (de)
CHLAMYDIA PROTEINE UND IHRE VERWENDUNG
Title (fr)
PROTEINES DE CHLAMYDIA ET LEURS UTILISATIONS
Publication
Application
Priority
- US 9908744 W 19990420
- US 8243898 P 19980420
- US 8258898 P 19980421
- US 8645098 P 19980522
Abstract (en)
[origin: WO9953948A1] Certain Chlamydia proteins have been found to be infection-specific and to be associated primarily with the vegetative Reticulate Body form of Chlamydia rather than with the refractile Elementary Body form of Chlamydia. The invention includes a vaccine directed against the Reticulate Body form of Chlamydia comprising one or more infection-specific proteins, or fraction thereof; a method of using such a vaccine; a method of production of such a vaccine; a method for detection of infection-specific antibodies in a biological specimen; a method for detection of infection-specific antigens in a biological specimen and a method of using therapeutic agents specifically directed against infection-specific peptides, or the genes that code for such peptides, to treat chlamydial infection. The invention also includes the IncB, and IncC proteins of C. psittaci, and nucleotides encoding these proteins, and the TroA, TroB and p242 proteins of C. trachomatis, and the nucleotides that encode these polypeptides.
IPC 1-7
IPC 8 full level
A61P 31/04 (2006.01); C07K 14/295 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
A61P 31/04 (2018.01); C07K 14/295 (2013.01); A61K 39/00 (2013.01); G01N 2333/295 (2013.01)
Citation (search report)
- [E] WO 9928475 A2 19990610 - GENSET SA [FR], et al & DATABASE EMBL [online] 7 October 1999 (1999-10-07), GRIFFAIS, R.: "C. trachomatis protein", XP002288811, retrieved from EBI accession no. AAY36954 Database accession no. AAY36954
- [E] WO 0034483 A2 20000615 - CORIXA CORP [US], et al & DATABASE EMBL [online] 2 February 2001 (2001-02-02), PROBST, P- ET AL., XP002288812, retrieved from EBI accession no. AAA64810 Database accession no. AAA64810
- [PX] BANNANTINE J P ET AL: "USE OF A PRIMATE MODEL SYSTEM TO IDENTIFY CHLAMYDIA TRACHOMATIS PROTEIN ANTIGENS RECOGNIZED UNIQUELY IN THE CONTEXT OF INFECTION", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB, vol. 145, no. 8, 1999, pages 2077 - 2085, XP001018896, ISSN: 1350-0872
- [A] ROCKEY D D ET AL: "CLONING AND CHARACTERIZATION OF A CHLAMYDIA PSITTACI GENE CODING FOR A PROTEIN LOCALIZED IN THE INCLUSION MEMBRANE OF INFECTED CELLS", MOLECULAR MICROBIOLOGY, BLACKWELL SCIENTIFIC, OXFORD, GB, vol. 15, no. 4, 1995, pages 617 - 626, XP000870116, ISSN: 0950-382X
- [A] ROCKEY D D ET AL: "Protein antigens of Chlamydia psittaci present in infected cells but not detected in the infectious elementary body", INFECTION AND IMMUNITY, vol. 62, no. 1, 1994, pages 106 - 112, XP001166991, ISSN: 0019-9567
- See also references of WO 9953948A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9953948 A1 19991028; AU 3659099 A 19991108; AU 754122 B2 20021107; CA 2326002 A1 19991028; EP 1073458 A1 20010207; EP 1073458 A4 20050112
DOCDB simple family (application)
US 9908744 W 19990420; AU 3659099 A 19990420; CA 2326002 A 19990420; EP 99918748 A 19990420