EP 1073644 A1 20010207 - SOLID SUPPORTED SYNTHESIS OF SULFONATED 2-OXOPIPERAZINES
Title (en)
SOLID SUPPORTED SYNTHESIS OF SULFONATED 2-OXOPIPERAZINES
Title (de)
FESTE TRÄGERSYNTHESE VON SULFONIERTEN 2-OXOPIPERAZINEN
Title (fr)
SYNTHESE SUR SUPPORT SOLIDE DE 2-OXOPIPERAZINES SULFONEES
Publication
Application
Priority
- US 9909091 W 19990427
- US 8346898 P 19980429
Abstract (en)
[origin: WO9955684A1] The subject invention involves processes for making 2-oxopiperazine and homologous compounds using a solid support resin by (a) removing the protecting group from a N-protected amino acid ester of the resin (if present), (b) reacting the resulting unprotected resin ester with a sulfonyl chloride, (c) reacting the resulting intermediate with a N-protected amino alcohol, (d) removing the N-protecting group from the N from the amino alcohol, and (e) cleaving/cyclizing the product from the resin.
IPC 1-7
IPC 8 full level
C07D 241/08 (2006.01); C07D 243/08 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP)
C07D 241/08 (2013.01); C07D 243/08 (2013.01); C07D 487/04 (2013.01); Y02P 20/55 (2015.11)
Citation (search report)
See references of WO 9955684A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9955684 A1 19991104; AU 3764399 A 19991116; CA 2328934 A1 19991104; EP 1073644 A1 20010207; IL 139121 A0 20011125; JP 2002513010 A 20020508; NO 20005303 D0 20001020; NO 20005303 L 20001220
DOCDB simple family (application)
US 9909091 W 19990427; AU 3764399 A 19990427; CA 2328934 A 19990427; EP 99920061 A 19990427; IL 13912199 A 19990427; JP 2000545844 A 19990427; NO 20005303 A 20001020