Global Patent Index - EP 1073644 A1

EP 1073644 A1 2001-02-07 - SOLID SUPPORTED SYNTHESIS OF SULFONATED 2-OXOPIPERAZINES

Title (en)

SOLID SUPPORTED SYNTHESIS OF SULFONATED 2-OXOPIPERAZINES

Title (de)

FESTE TRÄGERSYNTHESE VON SULFONIERTEN 2-OXOPIPERAZINEN

Title (fr)

SYNTHESE SUR SUPPORT SOLIDE DE 2-OXOPIPERAZINES SULFONEES

Publication

EP 1073644 A1 (EN)

Application

EP 99920061 A

Priority

  • US 9909091 W
  • US 8346898 P

Abstract (en)

[origin: WO9955684A1] The subject invention involves processes for making 2-oxopiperazine and homologous compounds using a solid support resin by (a) removing the protecting group from a N-protected amino acid ester of the resin (if present), (b) reacting the resulting unprotected resin ester with a sulfonyl chloride, (c) reacting the resulting intermediate with a N-protected amino alcohol, (d) removing the N-protecting group from the N from the amino alcohol, and (e) cleaving/cyclizing the product from the resin.

IPC 1-7 (main, further and additional classification)

C07D 241/08; C07D 243/08; C07D 487/04

IPC 8 full level (invention and additional information)

C07D 241/08 (2006.01); C07D 243/08 (2006.01); C07D 487/04 (2006.01)

CPC (invention and additional information)

C07D 487/04 (2013.01); C07D 241/08 (2013.01); C07D 243/08 (2013.01); Y02P 20/55 (2015.11)

Citation (search report)

See references of WO 9955684A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9955684 A1 19991104; AU 3764399 A 19991116; CA 2328934 A1 19991104; EP 1073644 A1 20010207; IL 139121 D0 20011125; JP 2002513010 A 20020508; NO 20005303 A 20001220; NO 20005303 D0 20001020

INPADOC legal status


2003-05-07 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20021105

2001-02-07 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001109

2001-02-07 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE