Global patent index - EP 1073663 A1

EP 1073663 A1 2001-02-07 - PREPARATION OF BETA-LACTAM ANTIBIOTICS IN THE PRESENCE OF UREA OR AMIDE

Title (en)

PREPARATION OF BETA-LACTAM ANTIBIOTICS IN THE PRESENCE OF UREA OR AMIDE

Title (de)

HERSTELLUNG VON BETA-LAKTAM-ANTIBIOTIKA IN ANWESENHEIT VON HARNSTOFF ODER AMID

Title (fr)

PREPARATION DE BETA-LACTAMINES EN PRESENCE D'UREE ET D'AMIDE

Publication

EP 1073663 A1 (EN)

Application

EP 99917237 A

Priority

  • EP 99917237 A
  • EP 98201399 A
  • NL 9900247 W

Abstract (en)

[origin: EP0953569A1] A process for the preparation of beta -lactam compounds has been described wherein before the addition of a base, urea or derivatives thereof and/or amide or derivatives has been added to (a) before an acid hydrolysis of the Dane salt coupling reaction mixture resulting from acylation of 6-amino-penicillanic acid, 7-amino-cephalosporanic acid or 7-amino-3'-desacetoxycephalosporanic acid and derivatives thereof at low temperature or to (b) a solution obtained by the addition of an acid to the crude beta -lactam antibiotic compound in water and/or one or more organic solvents.

IPC 1-7 (main, further and additional classification)

C07D 499/12; C07D 501/06

IPC 8 full level (invention and additional information)

C07D 499/00 (2006.01); C07D 499/12 (2006.01); C07D 501/00 (2006.01); C07D 501/06 (2006.01)

CPC (invention and additional information)

C07D 501/00 (2013.01); C07D 499/00 (2013.01)

Citation (search report)

See references of WO 9955709A1

Designated contracting state (EPC)

AT BE ES FR GB IT NL

EPO simple patent family

EP 0953569 A1 19991103; AU 3539699 A 19991116; BR 9910576 A 20010109; CN 1298407 A 20010606; EP 1073663 A1 20010207; ID 26414 A 20001221; PE 04362000 A1 20000520; TR 200003135 T2 20010321; WO 9955709 A1 19991104

INPADOC legal status

2002-06-12 [18W] WITHDRAWN

- Ref Legal Event Code: 18W

- Date of withdrawal: 20020423

2001-04-11 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20010227

2001-02-07 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000914

2001-02-07 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE ES FR GB IT NL