Global patent index - EP 1073671 A1

EP 1073671 A1 2001-02-07 - TARGETED GENE DELIVERY TO CELLS BY FILAMENTOUS BACTERIOPHAGE

Title (en)

TARGETED GENE DELIVERY TO CELLS BY FILAMENTOUS BACTERIOPHAGE

Title (de)

GEZIELTER GENTRANSPORT ZU ZELLEN DURCH FILAMENTOESEN BAKTERIOPHAGEN

Title (fr)

ADMINISTRATION DE GENES CIBLES DANS DES CELLULES AU MOYEN DE BACTERIOPHAGES FILAMENTEUX

Publication

EP 1073671 A1 (EN)

Application

EP 99919789 A

Priority

  • US 9907398 W
  • US 8295398 P
  • US 24940299 A

Abstract (en)

[origin: WO9955720A1] This invention provides methods specifically delivering and expressing heterologous nucleic acids in target cells. The methods generally involve providing a phage externally displaying a heterologues targeting protein (e.g., a scFv) and containing a heterologous nucleic acid; and contacting the target cell with the said phage whereby the phage is internalized into the cell and wherein the heterologous nucleic acid is transcribed, and optionally translated, within the cell.

IPC 1-7 (main, further and additional classification)

C07H 21/04; C12N 7/00; C12N 7/04; C12N 15/62; C12N 15/63; C12N 15/86

IPC 8 full level (invention and additional information)

A61K 47/48 (2006.01); C07K 14/01 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); A61K 47/48538 (2013.01); C07K 16/2863 (2013.01); C07K 16/2881 (2013.01); C07K 16/32 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/77 (2013.01); C07K 2319/02 (2013.01); C12N 2795/14022 (2013.01); C12N 2795/14043 (2013.01); C12N 2795/14045 (2013.01); C12N 2810/859 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9955720 A1 19991104; WO 9955720 A9 20000413; AU 3743299 A 19991116; AU 746040 B2 20020411; CA 2329908 A1 19991104; EP 1073671 A1 20010207; EP 1073671 A4 20040818

INPADOC legal status

2007-11-30 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Ref Legal Event Code: WD

- Ref Document Number: 1034717

- Country of Ref Document: HK

2005-04-13 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040923

2004-08-18 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20040705

2004-08-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7C 07H 21/04 A

2004-08-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7C 12N 7/00 B

2004-08-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7C 12N 7/04 B

2004-08-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7C 12N 15/63 B

2004-08-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7C 12N 15/86 B

2004-08-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7C 12N 15/62 B

2001-02-07 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20001123

2001-02-07 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE