EP 1073671 A1 20010207 - TARGETED GENE DELIVERY TO CELLS BY FILAMENTOUS BACTERIOPHAGE
Title (en)
TARGETED GENE DELIVERY TO CELLS BY FILAMENTOUS BACTERIOPHAGE
Title (de)
GEZIELTER GENTRANSPORT ZU ZELLEN DURCH FILAMENTOESEN BAKTERIOPHAGEN
Title (fr)
ADMINISTRATION DE GENES CIBLES DANS DES CELLULES AU MOYEN DE BACTERIOPHAGES FILAMENTEUX
Publication
Application
Priority
- US 9907398 W 19990423
- US 8295398 P 19980424
- US 24940299 A 19990212
Abstract (en)
[origin: WO9955720A1] This invention provides methods specifically delivering and expressing heterologous nucleic acids in target cells. The methods generally involve providing a phage externally displaying a heterologues targeting protein (e.g., a scFv) and containing a heterologous nucleic acid; and contacting the target cell with the said phage whereby the phage is internalized into the cell and wherein the heterologous nucleic acid is transcribed, and optionally translated, within the cell.
IPC 1-7
C07H 21/04; C12N 7/00; C12N 7/04; C12N 15/63; C12N 15/86; C12N 15/62
IPC 8 full level
A61K 47/48 (2006.01); C07K 14/01 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 47/6843 (2017.07); C07K 14/005 (2013.01); C07K 16/2863 (2013.01); C07K 16/2881 (2013.01); C07K 16/32 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/77 (2013.01); C07K 2319/02 (2013.01); C12N 2795/14022 (2013.01); C12N 2795/14043 (2013.01); C12N 2795/14045 (2013.01); C12N 2810/859 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9955720 A1 19991104; WO 9955720 A9 20000413; AU 3743299 A 19991116; AU 746040 B2 20020411; CA 2329908 A1 19991104; EP 1073671 A1 20010207; EP 1073671 A4 20040818
DOCDB simple family (application)
US 9907398 W 19990423; AU 3743299 A 19990423; CA 2329908 A 19990423; EP 99919789 A 19990423