Global Patent Index - EP 1073719 A2

EP 1073719 A2 20010207 - PROCESS FOR OBTAINING STEM CELLS

Title (en)

PROCESS FOR OBTAINING STEM CELLS

Title (de)

VERFAHREN ZUR HERSTELLUNG VON STAMMZELLEN

Title (fr)

PROCEDE D'OBTENTION DE CELLULES SOUCHES

Publication

EP 1073719 A2 20010207 (EN)

Application

EP 99918186 A 19990429

Priority

  • GB 9901333 W 19990429
  • GB 9809178 A 19980429

Abstract (en)

[origin: WO9955841A2] A method of obtaining a stem cell is described, comprising obtaining a somatic cell, which cell contains a gene coding for a marker which is differentially expressed in (a) desired stem cells and (b) cells other than desired stem cells; obtaining an enucleated oocyte; transferring the nucleus of the somatic cell into the enucleated oocyte to form a transgenic oocyte; culturing the transgenic oocyte to produce a culture of cells derived from the transgenic oocyte and identifying a cell of the culture that expresses the marker, thus indicating that the nucleus of that cell has been reprogrammed. Also described are assays for factors that can reprogram nuclei and stem cells obtained directly or indirectly using the nuclear reprogramming methods described.

IPC 1-7

C12N 5/06; C12N 5/08; C12Q 1/02

IPC 8 full level

C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/87 (2006.01); C12N 15/873 (2010.01); C12Q 1/02 (2006.01)

CPC (source: EP)

C12N 15/873 (2013.01); C12N 2503/00 (2013.01); C12N 2510/00 (2013.01); C12N 2517/04 (2013.01)

Citation (search report)

See references of WO 9955841A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9955841 A2 19991104; WO 9955841 A3 20000106; AU 3621299 A 19991116; CA 2329975 A1 19991104; EP 1073719 A2 20010207; GB 9809178 D0 19980701; IL 139322 A0 20011125; JP 2002512787 A 20020508; MX PA00010473 A 20020424

DOCDB simple family (application)

GB 9901333 W 19990429; AU 3621299 A 19990429; CA 2329975 A 19990429; EP 99918186 A 19990429; GB 9809178 A 19980429; IL 13932299 A 19990429; JP 2000545985 A 19990429; MX PA00010473 A 19990429