EP 1073754 A2 20010207 - PROCESS FOR THE PREPARATION OF PROTEIN MUTANTS HAVING LOWER ALLERGENIC RESPONSE IN HUMANS.
Title (en)
PROCESS FOR THE PREPARATION OF PROTEIN MUTANTS HAVING LOWER ALLERGENIC RESPONSE IN HUMANS.
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PROTEIN MUTANTEN MIT REDUZIERTER ALLERGENER WIRKUNG IN MENSCHEN.
Title (fr)
METHODES POUR PRODUIRE DES PROTEINES MUTANTES AVEC UNE REPONSE ALLERGENE PLUS FAIBLE CHEZ L'HOMME.
Publication
Application
Priority
- US 9908253 W 19990414
- US 6087298 A 19980415
Abstract (en)
[origin: EP1997897A1] The present invention relates to a novel improved protein mutant which produces low allergenic response in humans compared to the parent of that mutant. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein.
IPC 1-7
IPC 8 full level
A23K 1/165 (2006.01); A61K 38/46 (2006.01); A61P 37/08 (2006.01); C11D 3/386 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/54 (2006.01); C12N 15/09 (2006.01); C12N 15/57 (2006.01); C12N 15/63 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP KR US)
A61P 37/08 (2018.01 - EP); C12N 9/54 (2013.01 - EP KR US); G01N 33/505 (2013.01 - EP US); G01N 33/6878 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE
DOCDB simple family (publication)
WO 9953038 A2 19991021; WO 9953038 A3 20000210; AT E277189 T1 20041015; AT E452195 T1 20100115; AU 3645499 A 19991101; AU 752934 B2 20021003; BR 9909640 A 20001219; CA 2327311 A1 19991021; CA 2327311 C 20100316; CN 1297484 A 20010530; CN 1302113 C 20070228; CZ 20003789 A3 20010815; DE 69920434 D1 20041028; DE 69920434 T2 20051013; DE 69920434 T4 20060727; DE 69941827 D1 20100128; DK 1073754 T3 20050509; DK 1586649 T3 20100426; DK 1997897 T3 20130211; EP 1073754 A2 20010207; EP 1073754 B1 20040922; EP 1073754 B9 20050119; EP 1586649 A2 20051019; EP 1586649 A3 20051102; EP 1586649 B1 20091216; EP 1997897 A1 20081203; EP 1997897 B1 20121114; ES 2229703 T3 20050416; ES 2229703 T4 20060716; ES 2338319 T3 20100506; ID 26645 A 20010125; IL 138445 A0 20011031; IL 138445 A 20130530; JP 2002511251 A 20020416; JP 4447774 B2 20100407; KR 20010034776 A 20010425; MX PA05003288 A 20050908; MX PA05003289 A 20050908; NO 20005153 D0 20001013; NO 20005153 L 20001211; NZ 506926 A 20031031; NZ 524596 A 20040924; PL 343509 A1 20010827; US 2005137112 A1 20050623; US 6218165 B1 20010417; US 6596525 B1 20030722; US 6835550 B1 20041228
DOCDB simple family (application)
US 9908253 W 19990414; AT 04016880 T 19990414; AT 99918575 T 19990414; AU 3645499 A 19990414; BR 9909640 A 19990414; CA 2327311 A 19990414; CN 99805054 A 19990414; CZ 20003789 A 19990414; DE 69920434 A 19990414; DE 69920434 T 19990414; DE 69941827 T 19990414; DK 04016880 T 19990414; DK 08009499 T 19990414; DK 99918575 T 19990414; EP 04016880 A 19990414; EP 08009499 A 19990414; EP 99918575 A 19990414; ES 04016880 T 19990414; ES 99918575 T 19990414; ID 20002059 A 19990414; IL 13844500 A 20000913; IL 13844599 A 19990414; JP 2000543586 A 19990414; KR 20007011376 A 20001013; MX PA05003288 A 19990414; MX PA05003289 A 19990414; NO 20005153 A 20001013; NZ 50692699 A 19990414; NZ 52459699 A 19990414; PL 34350999 A 19990414; US 25550199 A 19990223; US 25550299 A 19990223; US 6087298 A 19980415; US 92409204 A 20040823