EP 1073765 A2 20010207 - GENE SCREENING METHODS AND RELATED ASSAYS
Title (en)
GENE SCREENING METHODS AND RELATED ASSAYS
Title (de)
GEN SCREENING-VERFAHREN UND TESTVERFAHREN
Title (fr)
PROCEDES DE CRIBLAGE DE GENES ET DOSAGES CORRESPONDANTS
Publication
Application
Priority
- CA 9900377 W 19990426
- US 8307798 P 19980427
Abstract (en)
[origin: WO9955906A2] The present invention relates to cell death genes, which are genes required for programmed cell death; mutant organisms, in which ectopic programmed cell death occurs in embryos to a greater than normal extent and agents which alter the ability to modulate programmed cell death of cells. A mutant form of Daktl, Daktl?q? in a Drosophila melanogaster has been identified. Daktl and its mammalian homolog, PKB are known to protect cells from undergoing apoptosis. A genetic screen for identifying genes related to programmed cell death by their ability to interact genetically with the mutant form of Daktl is described.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); C12Q 1/6897 (2018.01)
CPC (source: EP)
C12Q 1/6897 (2013.01)
Citation (search report)
See references of WO 9955906A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9955906 A2 19991104; WO 9955906 A3 20000316; AU 3591799 A 19991116; CA 2325823 A1 19991104; EP 1073765 A2 20010207; JP 2002512811 A 20020508
DOCDB simple family (application)
CA 9900377 W 19990426; AU 3591799 A 19990426; CA 2325823 A 19990426; EP 99917716 A 19990426; JP 2000546049 A 19990426