EP 1075252 A2 20010214 - SOLVENT/COSOLVENT FREE MICROEMULSION AND EMULSION PRECONCENTRATE DRUG DELIVERY SYSTEMS
Title (en)
SOLVENT/COSOLVENT FREE MICROEMULSION AND EMULSION PRECONCENTRATE DRUG DELIVERY SYSTEMS
Title (de)
MIKROEMULSION FREI VON LÖSUNGSMITTEL UND CO-LÖSUNGSMITTEL UND EMULSIONVORKONZENTRAT ALS WIRKSTOFF FREISETZUNGSSYTEMEN
Title (fr)
SYSTEMES D'APPORT DE MEDICAMENT DE PRECONCENTRE DE MICROEMULSION ET D'EMULSION DEPOURVUES DE SOLVANT/COSOLVANT
Publication
Application
Priority
- IE 9900031 W 19990507
- US 8451898 P 19980507
Abstract (en)
[origin: WO9956727A2] Self-emulsifying microemulsion or emulsion preconcentrate pharmaceutical compositions capable of forming an oil-in-water microemulsion or emulsion upon dilution with an aqueous solution are disclosed. The preconcentrate contains a therapeutically effective amount of a poorly water soluble therapeutic agent; a pharmaceutically effective amount of a low HLB oil component; and a surfactant system consisting essentially of at least one surfactant having an HLB of from about 10 to 20 and is substantially free or contains only minor amounts of a hydrophilic solvent system. Microemulsions or emulsions formed by diluting the self-emulsifying preconcentrate with an aqueous solution are also provided.
IPC 1-7
IPC 8 full level
A61K 9/107 (2006.01); A61K 9/48 (2006.01)
CPC (source: EP)
A61K 9/1075 (2013.01); A61K 9/4858 (2013.01); A61K 9/107 (2013.01)
Citation (search report)
See references of WO 9956727A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9956727 A2 19991111; WO 9956727 A3 20000302; AU 3843999 A 19991123; CA 2331640 A1 19991111; EP 1075252 A2 20010214; JP 2002513750 A 20020514
DOCDB simple family (application)
IE 9900031 W 19990507; AU 3843999 A 19990507; CA 2331640 A 19990507; EP 99921098 A 19990507; JP 2000546754 A 19990507