Global patent index - EP 1075254 A2

EP 1075254 A2 2001-02-14 - THE USE OF POLYAMINES IN THE TREATMENT OF DERMATOLOGICAL SYMPTOMS

Title (en)

THE USE OF POLYAMINES IN THE TREATMENT OF DERMATOLOGICAL SYMPTOMS

Title (de)

VERWENDUNG VON POLYAMINEN ZUR BEHANDLUNG DERMATOLOGISCHER SYMPTOMEN

Title (fr)

UTILISATION DE POLYAMINES DANS LE TRAITEMENT DE SYMPTOMES DERMATOLOGIQUES

Publication

EP 1075254 A2 (EN)

Application

EP 99913032 A

Priority

  • CA 9900285 W
  • CA 2234196 A

Abstract (en)

[origin: WO9951213A2] This invention provides for the use of non-toxic polyamines in the palliative treatment of chronic diseases and disorders of epithelial tissue. The effectiveness of treatment is evidenced by alleviation of symptoms and disorders manifesting in epithelial tissue such as skin, including pruritus, erythema, pain, parastesia and general discomfort, due to the topical administration of certain polyamines. Such symptoms arise from and/or are associated with chronic conditions such as: (i) skin diseases such as inflammatory dermatoses which include atopic and contact eczema, including xerosis such as dry skin and Winter itch; (ii) infection of epithelial tissue (eg. nasal, vulvar or anal passages) with trichomonas or fungi, anal fissures, fistula discharge, wound effluent, or surgical wound drainage; (iii) "secondary disease" in which epithelial tissue exhibits manifestations of the primary underlying disease such as AIDS, chicken pox and metabolic disorders (i.e., diabetes, hepatic and kidney dysfunction and hematopoesis); and (iv) disorders arising out of direct insult to the epithelial tissue following natural (local tumors, hemorrhoids) or surgical intervention and accompanying scar formation or radiation therapy.

IPC 1-7 (main, further and additional classification)

A61K 31/00

IPC 8 full level (invention and additional information)

A61P 17/00 (2006.01); A61K 31/13 (2006.01); A61K 31/132 (2006.01); A61K 31/155 (2006.01); A61P 29/00 (2006.01); A61P 37/08 (2006.01)

CPC (invention and additional information)

A61K 31/13 (2013.01); A61K 31/155 (2013.01)

Citation (search report)

See references of WO 9951213A3

Designated contracting state (EPC)

CH DE ES FR GB IT LI

EPO simple patent family

WO 9951213 A2 19991014; WO 9951213 A3 19991223; AU 3133399 A 19991025; EP 1075254 A2 20010214; IL 138732 D0 20011031; JP 2002510618 A 20020409; MX PA00009705 A 20030714

INPADOC legal status

2003-06-11 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20021204

2002-07-03 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020524

2001-02-14 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20001204

2001-02-14 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): CH DE ES FR GB IT LI