EP 1075547 A2 20010214 - MMP-9 GENE POLYMORPHISMS
Title (en)
MMP-9 GENE POLYMORPHISMS
Title (de)
POLYMORPHISMEN DES MMP-9 GENS
Title (fr)
POLYMORPHISMES DU GENE DE MMP-9
Publication
Application
Priority
- GB 9901447 W 19990507
- GB 9809764 A 19980507
Abstract (en)
[origin: WO9957315A2] A method of diagnosis or prognosis of a disease or characterisation of a genotype or genetic sequence which method comprises providing a nucleic acid sample and determining the nature of one or more genetic variants of an MMP-9 gene. Also described are oligonucleotides which hybridise to variants of a polymorphic sequence in the MMP-9 gene or its reverse complement. The method and oligonucleotides are of particular use for the diagnosis and prognosis of diseases characterised by metalloproteinase mediated remodelling, such as atherosclerosis, tumour invasion and metastasis, or inflammatory disease.
IPC 1-7
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6883 (2018.01)
CPC (source: EP)
C12Q 1/6883 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01)
Citation (search report)
See references of WO 9957315A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9957315 A2 19991111; WO 9957315 A3 20000302; AU 3938599 A 19991123; CA 2327538 A1 19991111; EP 1075547 A2 20010214; GB 9809764 D0 19980708
DOCDB simple family (application)
GB 9901447 W 19990507; AU 3938599 A 19990507; CA 2327538 A 19990507; EP 99922273 A 19990507; GB 9809764 A 19980507