EP 1076692 A2 20010221 - CRYSTALLIZABLE JNK COMPLEXES
Title (en)
CRYSTALLIZABLE JNK COMPLEXES
Title (de)
KRISTALLISIERBARE JNK KOMPLEXE
Title (fr)
COMPLEXES DE JNK CRISTALLISABLES
Publication
Application
Priority
- US 9909824 W 19990504
- US 8405698 P 19980504
Abstract (en)
[origin: WO9957253A2] The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of JNK3. A computer comprising such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to JNK3 or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of JNK3 or close structural homologues of the active site binding pockets.
IPC 1-7
IPC 8 full level
G01N 33/50 (2006.01); C12N 9/00 (2006.01); C12N 9/12 (2006.01); C12N 9/99 (2006.01); C12N 15/09 (2006.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01); G06F 17/30 (2006.01); G06F 17/50 (2006.01)
CPC (source: EP)
C12N 9/1205 (2013.01)
Citation (search report)
See references of WO 9957253A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9957253 A2 19991111; WO 9957253 A3 19991216; AU 3786899 A 19991123; EP 1076692 A2 20010221; JP 2002513562 A 20020514
DOCDB simple family (application)
US 9909824 W 19990504; AU 3786899 A 19990504; EP 99920350 A 19990504; JP 2000547209 A 19990504