Global Patent Index - EP 1076692 A2

EP 1076692 A2 2001-02-21 - CRYSTALLIZABLE JNK COMPLEXES

Title (en)

CRYSTALLIZABLE JNK COMPLEXES

Title (de)

KRISTALLISIERBARE JNK KOMPLEXE

Title (fr)

COMPLEXES DE JNK CRISTALLISABLES

Publication

EP 1076692 A2 (EN)

Application

EP 99920350 A

Priority

  • US 9909824 W
  • US 8405698 P

Abstract (en)

[origin: WO9957253A2] The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of JNK3. A computer comprising such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to JNK3 or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of JNK3 or close structural homologues of the active site binding pockets.

IPC 1-7 (main, further and additional classification)

C12N 9/12

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); C12N 9/00 (2006.01); C12N 9/12 (2006.01); C12N 9/99 (2006.01); C12N 15/09 (2006.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01); G06F 17/30 (2006.01); G06F 17/50 (2006.01)

CPC (invention and additional information)

C12N 9/1205 (2013.01)

Citation (search report)

See references of WO 9957253A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9957253 A2 19991111; WO 9957253 A3 19991216; AU 3786899 A 19991123; EP 1076692 A2 20010221; JP 2002513562 A 20020514

INPADOC legal status


2006-06-14 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20051122

2005-06-22 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050509

2001-02-21 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001123

2001-02-21 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE