Global Patent Index - EP 1077701 A1

EP 1077701 A1 2001-02-28 - ANTI-VIRAL COMPOUNDS

Title (en)

ANTI-VIRAL COMPOUNDS

Title (de)

ANTIVIRALE VERBINDUNGEN

Title (fr)

COMPOSES ANTI-VIRAUX

Publication

EP 1077701 A1 (EN)

Application

EP 98923565 A

Priority

US 9810299 W

Abstract (en)

[origin: WO9959587A1] The present invention relates to compounds of Formula (I), which inhibit the growth of picornaviruses, Hepatitus viruses, enteroviruses, cardioviruses, polioviruses, coxsackieviruses of the A and B groups, echo virus and Mengo virus. In said Formula, A is phenyl, pyridyl, substituted phenyl, substituted pyridyl, or benzyl; R is hydrogen, COR<4>, or COCF3; X is N-OH, O, or CHR<1>; R<1> is hydrogen, halo, CN, C1-C4 alkyl, -CCH, CO(C1-C4 alkyl), CO2(C1-C4 alkyl), or CONR<2>R<3>; R<2> and R<3> are independently hydrogen or C1-C4 alkyl; A' is hydrogen, halo, C1-C6 alkyl, benzyl, naphthyl, thienyl, furyl, pyridyl, pyrollyl, COR<4>, S(O)nR<4>, or a group of formula (II); R<4> is C1-C6 alkyl, phenyl, or substituted phenyl; n is 0, 1, or 2; R<5> is independently at each occurance hydrogen or halo; m is 1, 2, 3, or 4; and R<6> is hydrogen, halo, CF3, OH, CO2H, NH2, NO2, CONHOCH3, C1-C4 alkyl, or CO2(C1-C4 alkyl), C1-C4 alkoxy; or pharmaceutically acceptable salts thereof.

IPC 1-7 (main, further and additional classification)

A61K 31/44; C07D 471/04

IPC 8 full level (invention and additional information)

A61K 31/437 (2006.01); A61K 31/44 (2006.01); A61K 31/444 (2006.01); A61K 31/50 (2006.01); A61P 1/16 (2006.01); A61P 31/12 (2006.01); C07D 471/04 (2006.01)

IPC 8 main group level (invention and additional information)

A61K (2006.01)

CPC (invention and additional information)

C07D 471/04 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9959587 A1 19991125; AU 7583098 A 19991206; BR 9815899 A 20010220; CA 2332403 A1 19991125; CN 1292697 A 20010425; CZ 20004278 A3 20010516; CZ 289425 B6 20020116; EP 1077701 A1 20010228; EP 1077701 A4 20020320; HU 0102117 A2 20011228; IL 139166 D0 20011125; JP 2002515433 A 20020528; NO 20005795 A 20010118; NO 20005795 D0 20001116; SK 17482000 A3 20050304; TR 200003414 T2 20010321

INPADOC legal status


2004-06-16 [18D] DEEMED TO BE WITHDRAWN

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2003-09-17 [17Q] FIRST EXAMINATION REPORT

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2002-03-20 [A4] SUPPLEMENTARY SEARCH REPORT

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2002-03-20 [AK] DESIGNATED CONTRACTING STATES:

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2001-02-28 [17P] REQUEST FOR EXAMINATION FILED

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2001-02-28 [AK] DESIGNATED CONTRACTING STATES:

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2001-02-28 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

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- Free Format Text: AL PAYMENT 20001120;LT PAYMENT 20001120;LV PAYMENT 20001120;RO PAYMENT 20001120;SI PAYMENT 20001120