EP 1077705 A4 20020417 - POTASSIUM CHANNEL AGONISTS
Title (en)
POTASSIUM CHANNEL AGONISTS
Title (de)
KALIUMKANALAGONISTEN
Title (fr)
AGONISTES DU CANAL POTASSIUM
Publication
Application
Priority
- US 9910264 W 19990511
- US 8556298 P 19980515
Abstract (en)
[origin: WO9959594A1] This application discloses a method of treating cardiac ventricular arrhythmias and repolarization abnormalities associated with long QT syndrome and/or congestive heart failure comprising the administration of an agonist of the slowly activating cardiac delayed rectifier potassium current (IKs).
IPC 1-7
IPC 8 full level
C07D 487/10 (2006.01); A61K 31/438 (2006.01); A61K 31/5513 (2006.01); A61K 31/5517 (2006.01); A61K 45/00 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/06 (2006.01); A61P 43/00 (2006.01); C07D 403/06 (2006.01); C07D 491/107 (2006.01)
CPC (source: EP)
A61K 31/438 (2013.01); A61K 31/5513 (2013.01); A61K 31/5517 (2013.01); A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/06 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
- [X] WO 9514470 A1 19950601 - MERCK & CO INC [US], et al
- [XD] US 5633247 A 19970527 - BALDWIN JOHN J [US], et al
- [X] WILLIAM WM MUIR ET AL: "Antiarrhythmic effects of diazepam during coronary artery occlusion in dogs", AM. J. VET. RES., vol. 36, no. 8, 1975, pages 1203 - 1206, XP001027631
- [XP] SALATA J. ET AL: "A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents", MOLECULAR PHARMACOLOGY, vol. 54, no. 1, July 1998 (1998-07-01), pages 220 - 229, XP001027554
- [XP] SANGUINETTI M C, JURKIEWICZ N., SALATA J.: "Novel benzodiazepines that modulate slow delayed rectifier K channels", NAUNYN-SCHMIEDERBERGS ARCHIVES OF PHARMACOLOGY, vol. 358, no. 1(1), September 1998 (1998-09-01), pages sf45, XP001026937
- See references of WO 9959594A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9959594 A1 19991125; AU 3897299 A 19991206; AU 747340 B2 20020516; AU 747340 C 20030724; CA 2329916 A1 19991125; EP 1077705 A1 20010228; EP 1077705 A4 20020417; JP 2002515436 A 20020528
DOCDB simple family (application)
US 9910264 W 19990511; AU 3897299 A 19990511; CA 2329916 A 19990511; EP 99921866 A 19990511; JP 2000549259 A 19990511