Global Patent Index - EP 1077705 A4

EP 1077705 A4 20020417 - POTASSIUM CHANNEL AGONISTS

Title (en)

POTASSIUM CHANNEL AGONISTS

Title (de)

KALIUMKANALAGONISTEN

Title (fr)

AGONISTES DU CANAL POTASSIUM

Publication

EP 1077705 A4 20020417 (EN)

Application

EP 99921866 A 19990511

Priority

  • US 9910264 W 19990511
  • US 8556298 P 19980515

Abstract (en)

[origin: WO9959594A1] This application discloses a method of treating cardiac ventricular arrhythmias and repolarization abnormalities associated with long QT syndrome and/or congestive heart failure comprising the administration of an agonist of the slowly activating cardiac delayed rectifier potassium current (IKs).

IPC 1-7

A61K 31/55; A61K 31/453; A61P 9/00; A61P 9/04; A61P 9/06

IPC 8 full level

C07D 487/10 (2006.01); A61K 31/438 (2006.01); A61K 31/5513 (2006.01); A61K 31/5517 (2006.01); A61K 45/00 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/06 (2006.01); A61P 43/00 (2006.01); C07D 403/06 (2006.01); C07D 491/107 (2006.01)

CPC (source: EP)

A61K 31/438 (2013.01); A61K 31/5513 (2013.01); A61K 31/5517 (2013.01); A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/06 (2017.12); A61P 43/00 (2017.12)

Citation (search report)

  • [X] WO 9514470 A1 19950601 - MERCK & CO INC [US], et al
  • [XD] US 5633247 A 19970527 - BALDWIN JOHN J [US], et al
  • [X] WILLIAM WM MUIR ET AL: "Antiarrhythmic effects of diazepam during coronary artery occlusion in dogs", AM. J. VET. RES., vol. 36, no. 8, 1975, pages 1203 - 1206, XP001027631
  • [XP] SALATA J. ET AL: "A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents", MOLECULAR PHARMACOLOGY, vol. 54, no. 1, July 1998 (1998-07-01), pages 220 - 229, XP001027554
  • [XP] SANGUINETTI M C, JURKIEWICZ N., SALATA J.: "Novel benzodiazepines that modulate slow delayed rectifier K channels", NAUNYN-SCHMIEDERBERGS ARCHIVES OF PHARMACOLOGY, vol. 358, no. 1(1), September 1998 (1998-09-01), pages sf45, XP001026937
  • See references of WO 9959594A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9959594 A1 19991125; AU 3897299 A 19991206; AU 747340 B2 20020516; AU 747340 C 20030724; CA 2329916 A1 19991125; EP 1077705 A1 20010228; EP 1077705 A4 20020417; JP 2002515436 A 20020528

DOCDB simple family (application)

US 9910264 W 19990511; AU 3897299 A 19990511; CA 2329916 A 19990511; EP 99921866 A 19990511; JP 2000549259 A 19990511