Global patent index - EP 1078039 A2

EP 1078039 A2 2001-02-28 - METHOD FOR CARRYING OUT A MEASUREMENT OF THE INTERACTION OF CHEMICALS WITH CELLS

Title (en)

METHOD FOR CARRYING OUT A MEASUREMENT OF THE INTERACTION OF CHEMICALS WITH CELLS

Title (de)

VERFAHREN ZUR DURCHFÜHRUNG EINER MESSUNG DER INTERAKTION VON CHEMIKALIEN MIT ZELLEN

Title (fr)

PROCEDE POUR LA REALISATION D'UNE MESURE DE L'INTERACTION DE PRODUITS CHIMIQUES AVEC DES CELLULES

Publication

EP 1078039 A2 (DE)

Application

EP 99934492 A

Priority

  • DE 9901443 W
  • DE 19822827 A

Abstract (en)

[origin: WO9960094A2] The invention relates to a relates to a method for determining the interaction of chemicals with cells in a reactor, e.g. in a fixed-bed reactor or in a fluid-bed reactor. To this end, a signal is measured which is produced by one of the components affected during the reaction. The signal is suited for being detected by a detection system situated outside of the reactor. The component which produces the signal can be the chemical itself in which case it can concern the analysis of the pharmacokinetic characteristics of the chemical. An additional possibility relates to the analysis of an influence of the chemical on processes within the cell. A device for carrying out the inventive method comprises a reactor for accommodating the cells, a circulation system, control units for monitoring the composition of the medium, a system for gassing the medium, an entry for the chemical and at least one detection system for detecting the interaction.

IPC 1-7 (main, further and additional classification)

C12M 1/34; C12M 1/40

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); C12M 1/34 (2006.01); C12M 1/40 (2006.01); C12Q 1/02 (2006.01); G01N 33/15 (2006.01)

CPC (invention and additional information)

C12M 25/18 (2013.01); B01J 19/2465 (2013.01); G01N 33/5008 (2013.01); B01J 2219/00094 (2013.01); B01J 2219/00177 (2013.01); B01J 2219/00186 (2013.01)

Citation (search report)

See references of WO 9960094A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9960094 A2 19991125; WO 9960094 A3 20000316; DE 19822827 A1 20010118; EP 1078039 A2 20010228; JP 2002515589 A 20020528

INPADOC legal status

2002-06-19 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20011128

2001-07-04 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20010517

2001-02-28 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20001016

2001-02-28 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE