EP 1078075 A2 20010228 - RECOMBINANT (ALPHA)-L-IDURONIDASE, METHODS FOR PRODUCING AND PURIFYING THE SAME AND METHODS FOR TREATING DISEASES CAUSED BY DEFICIENCIES THEREOF
Title (en)
RECOMBINANT (ALPHA)-L-IDURONIDASE, METHODS FOR PRODUCING AND PURIFYING THE SAME AND METHODS FOR TREATING DISEASES CAUSED BY DEFICIENCIES THEREOF
Title (de)
REKOMBINANTE (ALPHA)-L-IDURONIDASE, DEREN HERSTELLUNGS- UND AUFREINIGUNGS-VERFAHREN, UND VERFAHREN ZUR BEHANDLUNG VON DURCH DIESE HERVORGERUFENE MANGELERKRANKUNGEN
Title (fr)
(ALPHA)-L-IDURONIDASE RECOMBINEE, PROCEDES DE PRODUCTION ET DE PURIFICATION DE CELLE-CI ET METHODES DE TRAITEMENT DE MALADIES DUES A DES DEFICITS EN CELLE-CI
Publication
Application
Priority
- US 9910102 W 19990507
- US 7820998 A 19980513
- US 17097798 A 19981013
Abstract (en)
[origin: WO9958691A2] The present invention provides a recombinant alpha -L-iduronidase and biologically active fragments and mutants thereof, methods to produce and purify this enzyme as well as methods to treat certain genetic disorders including alpha -L-iduronidase deficiency and mucopolysaccharidosis I (MPS I).
IPC 1-7
C12N 15/56; C12N 15/85; C12N 9/24; C12N 5/00; C12N 5/10; A61K 38/47
IPC 8 full level
A61K 38/46 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01); C12N 1/04 (2006.01); C12N 5/10 (2006.01); C12N 9/24 (2006.01); C12N 15/09 (2006.01); C12N 15/56 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C12N 9/2402 (2013.01); C12Y 302/01076 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9958691A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9958691 A2 19991118; WO 9958691 A3 20000217; AU 4072499 A 19991129; BR 9910323 A 20010130; CA 2328518 A1 19991118; CN 1300323 A 20010620; EP 1078075 A2 20010228; IL 139616 A0 20020210; JP 2002514429 A 20020521
DOCDB simple family (application)
US 9910102 W 19990507; AU 4072499 A 19990507; BR 9910323 A 19990507; CA 2328518 A 19990507; CN 99806064 A 19990507; EP 99924155 A 19990507; IL 13961699 A 19990507; JP 2000548482 A 19990507