EP 1078079 A4 20020313 - METHODS OF FORMING PROTEIN-LINKED LIPIDIC MICROPARTICLES, AND COMPOSITIONS THEREOF
Title (en)
METHODS OF FORMING PROTEIN-LINKED LIPIDIC MICROPARTICLES, AND COMPOSITIONS THEREOF
Title (de)
METHODEN ZUR GESTALTUNG VON PROTEINGEBUNDENEN LIPIDISCHEN MIKROPARTIKELN UND VERBINDUNGEN DAMIT
Title (fr)
PROCEDES DE FORMATION DE MICROPARTICULES LIPIDIQUES LIEES A DES PROTEINES ET LEURS COMPOSITIONS
Publication
Application
Priority
- US 9910375 W 19990511
- US 7661898 A 19980512
Abstract (en)
[origin: EP1724353A2] The present invention relates to lipidic microparticles with attached proteins which have been first conjugated to linker molecules having a hydrophilic polymer domain and a hydrophobic domain capable of stable association with the microparticle, or proteins which have been engineered to contain a hydrophilic domain and a lipid moiety permitting stable association with the microparticle.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 47/10 (2006.01); A61K 47/34 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/88 (2006.01)
CPC (source: EP US)
A61K 9/0019 (2013.01 - EP US); A61K 9/1272 (2013.01 - EP US); A61K 47/10 (2013.01 - EP US); A61K 47/542 (2017.08 - EP US); A61K 47/543 (2017.08 - EP US); A61K 47/6849 (2017.08 - EP US); A61K 47/6911 (2017.08 - EP US); A61K 47/6913 (2017.08 - EP US); A61K 48/00 (2013.01 - EP US); A61K 48/0041 (2013.01 - EP US); B82Y 5/00 (2013.01 - EP US); C07H 21/00 (2013.01 - EP US); C12N 15/88 (2013.01 - EP US)
Citation (search report)
- [A] WO 9738731 A1 19971023 - UNIV CALIFORNIA [US]
- [T] WO 9820857 A1 19980522 - UNIV CALIFORNIA [US]
- [XD] ZALIPSKY S ET AL: "POLY(ETHYLENE GLYCOL)-GRAFTED LIPOSOMES WITH OLIGOPEPTIDE OR OLIGOSACCHARIDE LIGANDS APPENDED TO THE TERMINI OF THE POLYMER CHAINS", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 8, no. 2, 1997, pages 111 - 118, XP000886841, ISSN: 1043-1802
- [A] KIRPOTIN D ET AL: "STERICALLY STABILIZED ANTI-HER2 IMMUNOLIPOSOMES: DESIGN AND TARGETING TO HUMAN BREAST CANCER CELLS IN VITRO", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 36, no. 1, 1997, pages 66 - 75, XP002927736, ISSN: 0006-2960
- [A] ADAMS G P ET AL: "HIGHLY SPECIFIC IN VIVO TUMOR TARGETING BY MONOVALENT AND DIVALENT FORMS OF 741F8 ANTI-C-ERBB-2 SINGLE-CHAIN FV", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 53, no. 17, 1 September 1993 (1993-09-01), pages 4026 - 4034, XP000891217, ISSN: 0008-5472
- [A] STORM G. ET AL.: "Immunoliposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of anticancer prodrugs.", ADV. DRUG DELIV. REV., vol. 24, 1997, pages 225 - 231, XP000826543
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9958694 A1 19991118; AT E377082 T1 20071115; AU 3983499 A 19991129; AU 770111 B2 20040212; CA 2330741 A1 19991118; CA 2330741 C 20130813; DE 69937450 D1 20071213; DE 69937450 T2 20080821; EP 1078079 A1 20010228; EP 1078079 A4 20020313; EP 1078079 B1 20071031; EP 1724353 A2 20061122; EP 1724353 A3 20070404; ES 2296391 T3 20080416; JP 2002514432 A 20020521; JP 2010031028 A 20100212; JP 4427186 B2 20100303; US 2002001612 A1 20020103; US 2003003143 A1 20030102; US 2004209366 A1 20041021; US 2006147513 A1 20060706; US 6210707 B1 20010403; US 6528087 B2 20030304; US 6803053 B2 20041012; US 7022336 B2 20060404
DOCDB simple family (application)
US 9910375 W 19990511; AT 99922950 T 19990511; AU 3983499 A 19990511; CA 2330741 A 19990511; DE 69937450 T 19990511; EP 06008157 A 19990511; EP 99922950 A 19990511; ES 99922950 T 19990511; JP 2000548485 A 19990511; JP 2009226639 A 20090930; US 17793902 A 20020621; US 36398606 A 20060227; US 76510701 A 20010116; US 7661898 A 19980512; US 84798204 A 20040517