Global Patent Index - EP 1079920 A1

EP 1079920 A1 2001-03-07 - DEVICE AND METHOD FOR PRODUCING A SYSTEM OF CHAIN MOLECULES ON A SUPPORT MATERIAL

Title (en)

DEVICE AND METHOD FOR PRODUCING A SYSTEM OF CHAIN MOLECULES ON A SUPPORT MATERIAL

Title (de)

VORRICHTUNG UND VERFAHREN ZUR HERSTELLUNG EINER ANORDNUNG VON KETTENMOLEKÜLEN AUF EINEM TRÄGERMATERIAL

Title (fr)

DISPOSITIF ET PROCEDE POUR PRODUIRE UN ENSEMBLE DE MOLECULES LINEAIRES SUR UN MATERIAU SUPPORT

Publication

EP 1079920 A1 (DE)

Application

EP 99920827 A

Priority

  • DE 19819735 A
  • EP 9902958 W

Abstract (en)

[origin: WO9956865A1] The invention relates to a method, a device and the use of a device for producing a support material having chain molecules synthesized in synthesis fields, especially oligonucleotides which are complementary to segments of carriers of genetic information. According to the invention, after a synthesis run for synthesizing chain molecules (21) in a sequence of synthesis fields (1 to 16), at least one additional synthesis run is carried out, during which chain elements (n4 to n15) of one base-type sequence are linked to the chain molecules (21) synthesized during the preceding synthesis run or during each preceding synthesis run and comprising other chain elements (N1 to N12; N9 to N17) of another base-type sequence. The delivery of chain elements (N1 to N17; n4 to n15) to the synthesis fields (1 to 16) in the synthesis runs corresponds to the predetermined succession of chain elements (N1 to N17; n4 to n15) in the chain molecules (21) to be synthesized. The groups of synthesis fields (27) assigned to synthesis regions (1 to 16) are during each synthesis cycle displaced by one synthesis field (1 to 16), always moving in the same direction. In this way it is possible efficiently to synthesize, for example, chain molecules (21) which are complementary to at least parts of segments (20) of carriers of genetic information, with groups of chain elements (N1 to N17; n4 to n15) so as to obtain different base-type sequences.

IPC 1-7 (main, further and additional classification)

B01J 19/00; C07H 21/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); B01J 19/00 (2006.01); C07H 21/00 (2006.01); C12M 1/00 (2006.01); G01N 37/00 (2006.01); C40B 40/06 (2006.01); C40B 60/14 (2006.01)

CPC (invention and additional information)

C07H 21/00 (2013.01); B01J 19/0046 (2013.01); B01J 2219/0043 (2013.01); B01J 2219/00475 (2013.01); B01J 2219/00518 (2013.01); B01J 2219/00533 (2013.01); B01J 2219/0059 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00605 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00621 (2013.01); B01J 2219/00626 (2013.01); B01J 2219/00657 (2013.01); B01J 2219/00689 (2013.01); B01J 2219/00695 (2013.01); B01J 2219/00722 (2013.01); C07B 2200/11 (2013.01); C40B 40/06 (2013.01); C40B 60/14 (2013.01)

Citation (search report)

See references of WO 9956865A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9956865 A1 19991111; AU 3825899 A 19991123; DE 19819735 A1 19991104; EP 1079920 A1 20010307; JP 2002513549 A 20020514

INPADOC legal status


2004-05-12 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031031

2001-03-07 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001012

2001-03-07 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2001-03-07 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: RO PAYMENT 20001012;SI PAYMENT 20001012