EP 1080066 A4 20041222 - BIOREDUCTIVE CYTOTOXIC AGENTS
Title (en)
BIOREDUCTIVE CYTOTOXIC AGENTS
Title (de)
BIOREDUKTIVE CYTOTOXISCHE MITTEC
Title (fr)
AGENTS CYTOTOXIQUES BIOREDUCTEURS
Publication
Application
Priority
- US 9911199 W 19990520
- US 8365298 A 19980522
- US 8642998 P 19980522
Abstract (en)
[origin: WO9961409A1] A compound which consists of a proactive alkylating moiety containing an electron-withdrawing group, a bioreductive moiety containing at least two double bonds, and a linker joining the proactive alkylating moiety and the bioreductive moiety.
IPC 1-7
C07C 229/60; C07D 307/42; C07D 209/08; C07D 235/12; C07D 307/79; C07C 229/56; C07C 229/64; C07D 209/12; C07D 295/10
IPC 8 full level
A61K 31/196 (2006.01); A61K 31/235 (2006.01); A61K 31/343 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/4184 (2006.01); A61K 31/5355 (2006.01); A61K 31/5375 (2006.01); A61P 35/00 (2006.01); C07D 295/08 (2006.01); A61P 43/00 (2006.01); C07C 37/02 (2006.01); C07C 50/02 (2006.01); C07C 229/56 (2006.01); C07C 229/60 (2006.01); C07C 229/64 (2006.01); C07C 229/66 (2006.01); C07C 233/54 (2006.01); C07C 271/28 (2006.01); C07D 209/04 (2006.01); C07D 209/08 (2006.01); C07D 209/12 (2006.01); C07D 235/02 (2006.01); C07D 235/12 (2006.01); C07D 235/16 (2006.01); C07D 265/30 (2006.01); C07D 295/10 (2006.01); C07D 307/02 (2006.01); C07D 307/42 (2006.01); C07D 307/79 (2006.01)
IPC 8 main group level
C07C (2006.01)
CPC (source: EP KR)
A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07C 50/24 (2013.01 - KR); C07C 229/56 (2013.01 - EP); C07C 229/60 (2013.01 - EP); C07C 229/64 (2013.01 - EP); C07C 233/54 (2013.01 - EP); C07C 271/28 (2013.01 - EP); C07D 209/08 (2013.01 - EP); C07D 209/12 (2013.01 - EP); C07D 235/12 (2013.01 - EP); C07D 295/116 (2013.01 - EP); C07D 307/79 (2013.01 - EP); C07C 2601/02 (2017.05 - EP); C07C 2601/04 (2017.05 - EP); C07C 2601/16 (2017.05 - EP); C07C 2602/10 (2017.05 - EP)
Citation (search report)
- [A] WO 9622277 A1 19960725 - CANCER RES CAMPAIGN TECH [GB], et al
- [A] WO 9723456 A1 19970703 - BRITISH TECH GROUP [GB], et al
- [PA] WO 9820874 A1 19980522 - SUGEN INC [US]
- [A] WITIAK D.T. ET AL.: "Bis(bioreductive) alkylating agents: synthesis and biological activity in a nude mouse human carcinoma model.", JOURNAL OF MEDICINAL CHEMISTRY., vol. 26, no. 12, 1983, USAMERICAN CHEMICAL SOCIETY. WASHINGTON., pages 1679 - 1686, XP002302094
- See also references of WO 9961409A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9961409 A1 19991202; AU 4091399 A 19991213; AU 750381 B2 20020718; BR 9911066 A 20010213; CA 2332806 A1 19991202; CN 1302287 A 20010704; EP 1080066 A1 20010307; EP 1080066 A4 20041222; HR P20000794 A2 20011031; HU P0102932 A2 20011228; HU P0102932 A3 20021228; JP 2002516304 A 20020604; KR 20010074498 A 20010804; NO 20005880 D0 20001121; NO 20005880 L 20010109; PL 344257 A1 20011022
DOCDB simple family (application)
US 9911199 W 19990520; AU 4091399 A 19990520; BR 9911066 A 19990520; CA 2332806 A 19990520; CN 99806490 A 19990520; EP 99924405 A 19990520; HR P20000794 A 20001120; HU P0102932 A 19990520; JP 2000550818 A 19990520; KR 20007013155 A 20001122; NO 20005880 A 20001121; PL 34425799 A 19990520