Global Patent Index - EP 1080066 A4

EP 1080066 A4 2004-12-22 - BIOREDUCTIVE CYTOTOXIC AGENTS

Title (en)

BIOREDUCTIVE CYTOTOXIC AGENTS

Title (de)

BIOREDUKTIVE CYTOTOXISCHE MITTEC

Title (fr)

AGENTS CYTOTOXIQUES BIOREDUCTEURS

Publication

EP 1080066 A4 (EN)

Application

EP 99924405 A

Priority

  • US 9911199 W
  • US 8365298 A
  • US 8642998 P

Abstract (en)

[origin: WO9961409A1] A compound which consists of a proactive alkylating moiety containing an electron-withdrawing group, a bioreductive moiety containing at least two double bonds, and a linker joining the proactive alkylating moiety and the bioreductive moiety.

IPC 1-7 (main, further and additional classification)

C07C 229/60; C07C 229/56; C07C 229/64; C07D 209/08; C07D 209/12; C07D 235/12; C07D 295/10; C07D 307/42; C07D 307/79

IPC 8 full level (invention and additional information)

C07D 295/08 (2006.01); A61K 31/196 (2006.01); A61K 31/235 (2006.01); A61K 31/343 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/4184 (2006.01); A61K 31/5355 (2006.01); A61K 31/5375 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07C 37/02 (2006.01); C07C 50/02 (2006.01); C07C 229/56 (2006.01); C07C 229/60 (2006.01); C07C 229/64 (2006.01); C07C 229/66 (2006.01); C07C 233/54 (2006.01); C07C 271/28 (2006.01); C07D 209/04 (2006.01); C07D 209/08 (2006.01); C07D 209/12 (2006.01); C07D 235/02 (2006.01); C07D 235/12 (2006.01); C07D 235/16 (2006.01); C07D 265/30 (2006.01); C07D 295/10 (2006.01); C07D 307/02 (2006.01); C07D 307/42 (2006.01); C07D 307/79 (2006.01)

IPC 8 main group level (invention and additional information)

C07C (2006.01)

CPC (invention and additional information)

C07C 229/64 (2013.01); C07C 229/56 (2013.01); C07C 229/60 (2013.01); C07C 233/54 (2013.01); C07C 271/28 (2013.01); C07D 209/08 (2013.01); C07D 209/12 (2013.01); C07D 235/12 (2013.01); C07D 295/116 (2013.01); C07D 307/79 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2601/16 (2017.05); C07C 2602/10 (2017.05)

Citation (search report)

  • [A] WO 9622277 A1 19960725 - CANCER RES CAMPAIGN TECH [GB], et al
  • [A] WO 9723456 A1 19970703 - BRITISH TECH GROUP [GB], et al
  • [PA] WO 9820874 A1 19980522 - SUGEN INC [US]
  • [A] WITIAK D.T. ET AL.: "Bis(bioreductive) alkylating agents: synthesis and biological activity in a nude mouse human carcinoma model.", JOURNAL OF MEDICINAL CHEMISTRY., vol. 26, no. 12, 1983, USAMERICAN CHEMICAL SOCIETY. WASHINGTON., pages 1679 - 1686, XP002302094
  • See also references of WO 9961409A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9961409 A1 19991202; AU 4091399 A 19991213; AU 750381 B2 20020718; BR 9911066 A 20010213; CA 2332806 A1 19991202; CN 1302287 A 20010704; EP 1080066 A1 20010307; EP 1080066 A4 20041222; HR P20000794 A2 20011031; HU 0102932 A2 20011228; HU 0102932 A3 20021228; JP 2002516304 A 20020604; NO 20005880 A 20010109; NO 20005880 D0 20001121; PL 344257 A1 20011022

INPADOC legal status


2005-08-17 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20050127

2004-12-22 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20041108

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07C 229/60 A

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 307/42 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 209/08 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 235/12 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 307/79 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07C 229/56 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07C 229/64 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 209/12 B

2004-12-22 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 295/10 B

2001-03-07 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001222

2001-03-07 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-03-07 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL PAYMENT 20001222;LT PAYMENT 20001222;LV PAYMENT 20001222;MK PAYMENT 20001222;RO PAYMENT 20001222;SI PAYMENT 20001222