EP 1080110 A2 20010307 - USE OF ACTIVATED T CELLS, NERVOUS SYSTEM-SPECIFIC ANTIGENS FOR TREATING DISORDERS OF THE NEVROUS SYSTEM
Title (en)
USE OF ACTIVATED T CELLS, NERVOUS SYSTEM-SPECIFIC ANTIGENS FOR TREATING DISORDERS OF THE NEVROUS SYSTEM
Title (de)
VERWENDUNG VON AKTIVIERTEN T ZELLEN, NERVENSYSTEM-SPEZIFISCHEN ANTIGENE ZUR BEHANDLUND VON ERKRANKUNGEN DES NERVENSYSTEMS
Title (fr)
LYMPHOCYTES T ACTIVES, ANTIGENES SPECIFIQUES DU SYSTEME NERVEUX ET LEUR UTILISATION
Publication
Application
Priority
- IL 12455098 A 19980519
- US 9910953 W 19990519
- US 9814715 W 19980721
- US 21827798 A 19981222
Abstract (en)
[origin: WO9960021A2] Compositions and methods are provided for treating injury to or disease of the central or peripheral nervous system. In one embodiment, treatment is effected using activated T cells that recognize an antigen of the nervous system or a peptide derived therefrom or a derivative thereof to promote nerve regeneration or to prevent or inhibit neuronal degeneration within the nervous system. Treatment involves administering an NS-specific antigen or peptide derived therefrom or a derivative thereof, or a nucleotide sequence encoding said antigen or peptide, to promote nerve regeneration or to prevent or inhibit neuronal degeneration in the nervous system, either the central nervous system or the peripheral nervous system. The NS-specific activated T cells can be administered alone or in combination with NS-specific antigen or peptide derived therefrom or a derivative thereof or a nucleotide sequence encoding said antigen or peptide, or any combination thereof.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/711 (2006.01); A61K 35/26 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 39/00 (2006.01); A61P 25/28 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61K 38/1709 (2013.01); A61K 39/0007 (2013.01); A61K 39/4611 (2023.05); A61K 39/46432 (2023.05); A61P 25/28 (2018.01); A61K 48/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9960021 A2 19991125; WO 9960021 A3 20000615; CA 2328612 A1 19991125; EP 1080110 A2 20010307; JP 2003532618 A 20031105
DOCDB simple family (application)
US 9910953 W 19990519; CA 2328612 A 19990519; EP 99923190 A 19990519; JP 2000549639 A 19990519