EP 1080184 A1 20010307 - METHOD FOR ACTIVATING NATURAL KILLER (NK) CELLS
Title (en)
METHOD FOR ACTIVATING NATURAL KILLER (NK) CELLS
Title (de)
METHODEN ZUR AKTIVIERUNG VON NATÜRLICHEN KILLERZELLEN (NK)
Title (fr)
METHODES D'ACTIVATION DE CELLULES TUEUSES NATURELLES (NK)
Publication
Application
Priority
- FR 9900482 W 19990303
- FR 9802558 A 19980303
- FR 9810636 A 19980821
Abstract (en)
[origin: WO9945102A1] The invention concerns a method for activating natural killer cells which consists in contacting NK cells with dendritic cells in vitro, ex vivo or in vivo. The invention also concerns cell compositions, comprising in particular activated NK cells, NK cells-dendritic cells cocultures or dendritic cells, and their use for stimulating cytolitic activity of NK cells or natural immunity in vivo. The invention further concerns a factor stimulating the NK cells present in the membrane of dendritic cells, and media and factor(s) triggering dendritic cells and their use, whether separate or combined, stimulating NK activity, particularly in vivo. The invention can be used to control the activity of NK cells in vitro, ex vivo or in vivo, particularly in pathological conditions.
IPC 1-7
IPC 8 full level
C12M 1/00 (2006.01); A61K 31/00 (2006.01); A61K 35/15 (2015.01); A61K 35/26 (2006.01); A61K 38/18 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C12N 5/0783 (2010.01); C12N 5/0784 (2010.01); A61K 35/12 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP US)
A61K 35/15 (2013.01 - EP US); A61K 38/18 (2013.01 - EP US); A61K 39/4615 (2023.05 - EP); A61K 39/4622 (2023.05 - EP); A61K 39/4644 (2023.05 - EP); A61P 31/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 37/00 (2018.01 - EP); C12N 5/0639 (2013.01 - EP US); C12N 5/0646 (2013.01 - EP US); A61K 2039/5154 (2013.01 - US); A61K 2239/31 (2023.05 - EP); A61K 2239/38 (2023.05 - EP); C12N 2501/26 (2013.01 - EP US); C12N 2502/11 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9945102 A1 19990910; AU 3257999 A 19990920; AU 758622 B2 20030327; CA 2322712 A1 19990910; EP 1080184 A1 20010307; JP 3541140 B2 20040707; JP H11290068 A 19991026; TW 585915 B 20040501; US 6849452 B1 20050201
DOCDB simple family (application)
FR 9900482 W 19990303; AU 3257999 A 19990303; CA 2322712 A 19990303; EP 99937940 A 19990303; JP 5552899 A 19990303; TW 88103226 A 19990303; US 26051299 A 19990302