Global Patent Index - EP 1080186 A2

EP 1080186 A2 2001-03-07 - METHOD FOR ALTERING THE ACTIVITY OF PROTEINS OF THE PKA SIGNALING PATHWAY

Title (en)

METHOD FOR ALTERING THE ACTIVITY OF PROTEINS OF THE PKA SIGNALING PATHWAY

Title (de)

VERFAHREN ZUR MODIFIZIERUNG DER AKTIVITÄT VON PROTEINEN DER PKA SIGNALTRANSDUKTIONSKASKADE

Title (fr)

METHODE

Publication

EP 1080186 A2 (EN)

Application

EP 99925154 A

Priority

  • GB 9901680 W
  • NO 982419 A
  • US 11424098 P

Abstract (en)

[origin: WO9962315A2] The invention relates to methods of altering the activity of the PKA signaling pathway by altering, preferably inhibiting, the extent of phosphorylation of PKA substrates or downstream kinase substrates, particularly by the use of modified substrates, gene sequences encoding such modified substrates, vectors and host cells containing the gene sequence, inhibitors of substrate phosphorylation and use of the gene sequence, protein or inhibitors to alter the PKA signaling pathway, for example in treating immunosuppressive disorders or proliferative diseases.

IPC 1-7 (main, further and additional classification)

C12N 9/12

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/10 (2006.01); C12N 15/52 (2006.01); C12P 19/18 (2006.01); C12Q 1/02 (2006.01)

CPC (invention and additional information)

C12N 9/1051 (2013.01); A61K 38/1709 (2013.01); C12N 15/52 (2013.01); C12P 19/18 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9962315 A2 19991202; WO 9962315 A3 20000504; AU 4154499 A 19991213; AU 766674 B2 20031023; CA 2333159 A1 19991202; EP 1080186 A2 20010307; JP 2002516670 A 20020611; NZ 508359 A 20030725

INPADOC legal status


2007-06-27 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20061130

2005-03-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050114

2001-09-19 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: LAURAS AS

2001-03-07 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001219

2001-03-07 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-03-07 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20001219;LT PAYMENT 20001219;LV PAYMENT 20001219;MK PAYMENT 20001219;RO PAYMENT 20001219;SI PAYMENT 20001219