EP 1080371 A1 20010307 - METHOD AND MEANS FOR CARIES PREVENTION AND SUSCEPTIBILITY DETECTION

Title (en)

METHOD AND MEANS FOR CARIES PREVENTION AND SUSCEPTIBILITY DETECTION

Title (de)

VERFAHREN UND HILFSMITTEL ZUR VORBEUGE GEGEN KARIES UND BESTIMMUNG DER EMPFINDLICHKEIT

Title (fr)

PROCEDE ET MOYEN DE PREVENTION DES CARIES DENTAIRES ET DETECTION DE SENSIBILITE

Publication

EP 1080371 A1 20010307 (EN)

Application

EP 99930050 A 19990528

Priority

SE 9900930 W 19990528
SE 9801893 A 19980528

Abstract (en)

[origin: WO9961918A1] A method for identifying the susceptibility of a person to dental caries comprises the assay of one or several of: an agent having high binding capacity to Streptococcus mutans but low binding capacity to Actinomyces naeslundii, an agent having high binding capacity to S. mutans-binding agglutinin, an agent having high binding capacity to A. naeslundii. The agent having high binding capacity to Streptococcus mutans but low binding capacity to A. naeslundii comprises an allelic Db type of salivary acidic proline-rich molecules (acidic PRPs), a biologically active fragment or a genetic precursor thereof. A corresponding reagent is also identified. Also disclosed are a method and an agent for the prevention of caries, as well as labelled S. mutans and A. naeslundii and their use.

IPC 1-7

G01N 33/60; C07K 14/435; A61K 39/395; C12N 1/20

IPC 8 full level

A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 1/02 (2006.01); A61P 31/04 (2006.01); C07K 14/47 (2006.01); C07K 16/12 (2006.01); C12N 1/20 (2006.01); C12N 15/09 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/569 (2006.01); G01N 33/577 (2006.01)

CPC (source: EP)

A61P 1/02 (2017.12); A61P 31/04 (2017.12); G01N 33/56944 (2013.01); G01N 33/56955 (2013.01); A61K 2039/505 (2013.01)

Citation (search report)

See references of WO 9961918A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9961918 A1 19991202; BR 9910752 A 20011002; EP 1080371 A1 20010307; JP 2002516997 A 20020611; SE 9801893 D0 19980528

DOCDB simple family (application)

SE 9900930 W 19990528; BR 9910752 A 19990528; EP 99930050 A 19990528; JP 2000551263 A 19990528; SE 9801893 A 19980528