Global Patent Index - EP 1082104 A1

EP 1082104 A1 2001-03-14 - NOVEL POLY(METHYLIDENE MALONATE) MICROSPHERES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Title (en)

NOVEL POLY(METHYLIDENE MALONATE) MICROSPHERES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Title (de)

NEUE MIKROSPHÄREN AUF BASIS VON POLY(METHYLIDENMALONAT), DEREN HERSTELLUNGSVERFAHREN UND DIESE ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN

Title (fr)

NOUVELLES MICROSPHERES A BASE DE POLY(METHYLIDENE MALONATE), LEUR PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

Publication

EP 1082104 A1 (FR)

Application

EP 99915856 A

Priority

  • FR 9901005 W
  • FR 9805424 A

Abstract (en)

[origin: FR2778100A1] The invention concerns novel microspheres particularly useful in pharmaceutics as particulate vectors for carrying biologically active substances, in particular hydrophilic substances, for oral administration. The invention is characterised in that said microspheres consist of a support material continuous lattice wherein is optionally dispersed a substance, said support material containing at least 70 wt.% of a homopolymer consisting of recurrent units corresponding to general formula (I) wherein: R1 represents an alkyl group containing 1 to 6 carbon atoms or a (CH2)m - COOR3 group wherein m is an integer ranging between 1 and 5 and R3 represents an alkyl group having 1 to 6 carbon atoms; R2 represents an alkyl group having 1 to 6 carbon atoms; and n is an integer ranging between 1 and 5. The invention is useful in pharmaceutics.

IPC 1-7 (main, further and additional classification)

A61K 9/16

IPC 8 full level (invention and additional information)

A61K 9/16 (2006.01); A61K 9/50 (2006.01); A61K 38/00 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2006.01); C07K 17/08 (2006.01); C08F 122/14 (2006.01); C08J 3/14 (2006.01)

CPC (invention and additional information)

C08J 3/14 (2013.01); A61K 9/1635 (2013.01); A61K 9/1641 (2013.01); C08J 2335/00 (2013.01)

Citation (search report)

See references of WO 9955309A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

FR 2778100 A1 19991105; FR 2778100 B1 20010504; AR 019114 A1 20011226; AU 3428899 A 19991116; AU 752644 B2 20020926; BR 9910016 A 20010109; CA 2330481 A1 19991104; CN 1146408 C 20040421; CN 1303274 A 20010711; EP 1082104 A1 20010314; HU 0101649 A2 20020328; HU 0101649 A3 20021028; JP 2002513042 A 20020508; PL 343687 A1 20010827; RU 2227018 C2 20040420; SK 16312000 A3 20010409; US 6440461 B1 20020827; WO 9955309 A1 19991104

INPADOC legal status


2005-09-07 [18R] REFUSED

- Effective date: 20050416

2001-09-12 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010725

2001-03-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001020

2001-03-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE