Title (en)

HIV INTEGRASE INHIBITORS

Title (de)

HIV-INTEGRASEINHIBITOREN

Title (fr)

INHIBITEURS DE VIH INTEGRASE

Publication

EP 1082121 A1 20010314 (EN)

Application

EP 99926094 A 19990601

Priority

• GB 9815175 A 19980713
• US 9912093 W 19990601
• US 8782098 P 19980603

Abstract (en)

[origin: WO9962520A1] Certain six-membered aromatic and heteroaromatic-dioxo-butyric acid derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

IPC 1-7

A61K 31/535

IPC 8 full level

C07C 59/84 (2006.01); C07C 59/86 (2006.01); C07C 59/88 (2006.01); C07C 59/90 (2006.01); C07C 69/738 (2006.01); C07C 217/60 (2006.01); C07C 229/34 (2006.01); C07C 229/42 (2006.01); C07C 233/63 (2006.01); C07C 235/60 (2006.01); C07C 255/41 (2006.01); C07C 271/16 (2006.01); C07C 271/28 (2006.01); C07C 323/62 (2006.01); C07D 209/12 (2006.01); C07D 213/64 (2006.01); C07D 241/12 (2006.01); C07D 253/08 (2006.01); C07D 263/58 (2006.01); C07D 295/092 (2006.01); C07D 295/155 (2006.01); C07D 295/192 (2006.01); C07D 333/22 (2006.01)

CPC (source: EP)

C07C 59/84 (2013.01); C07C 59/86 (2013.01); C07C 59/88 (2013.01); C07C 59/90 (2013.01); C07C 69/738 (2013.01); C07C 217/60 (2013.01); C07C 229/34 (2013.01); C07C 229/42 (2013.01); C07C 233/63 (2013.01); C07C 235/60 (2013.01); C07C 255/41 (2013.01); C07C 271/16 (2013.01); C07C 271/28 (2013.01); C07C 323/62 (2013.01); C07D 209/12 (2013.01); C07D 213/64 (2013.01); C07D 241/12 (2013.01); C07D 253/08 (2013.01); C07D 263/58 (2013.01); C07D 295/088 (2013.01); C07D 295/155 (2013.01); C07D 295/192 (2013.01); C07D 333/22 (2013.01); C07C 2601/02 (2017.04); C07C 2601/04 (2017.04); C07C 2601/08 (2017.04); C07C 2602/08 (2017.04); C07C 2602/10 (2017.04)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9962520 A1 19991209; AU 4225499 A 19991220; CA 2333707 A1 19991209; EP 1082121 A1 20010314; EP 1082121 A4 20030205

DOCDB simple family (application)

US 9912093 W 19990601; AU 4225499 A 19990601; CA 2333707 A 19990601; EP 99926094 A 19990601