Global Patent Index - EP 1082334 A1

EP 1082334 A1 20010314 - ALG-2LP, ALG-2 LIKE MOLECULES AND USES THEREFOR

Title (en)

ALG-2LP, ALG-2 LIKE MOLECULES AND USES THEREFOR

Title (de)

ALG-2LP SOWIE ALG-2 ANALOGA UND IHRE VERWENDUNG

Title (fr)

MOLECULES DU TYPE ALG-2LP, ALG-2 ET UTILISATIONS DE CES DERNIERES

Publication

EP 1082334 A1 20010314 (EN)

Application

EP 99923016 A 19990513

Priority

  • US 9910581 W 19990513
  • US 8474998 A 19980526

Abstract (en)

[origin: WO9961459A1] The invention provides isolated nucleic acids molecules, designated hALG-2LP, sALG-2LP, and mALG-2LP nucleic acid molecules, which encode proteins involved in the modulation of programmed cell death. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing hALG-2LP, sALG-2LP, and mALG-2LP nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a hALG-2LP, sALG-2LP, and mALG-2LP gene has been introduced or disrupted. The invention still further provides isolated hALG-2LP, sALG-2LP, and mALG-2LP proteins, fusion proteins, antigenic peptides and anti-hALG-2LP, sALG-2LP, and mALG-2LP antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

IPC 1-7

C07H 21/04; A61K 38/00; C07K 5/00; C07K 7/00; C07K 16/00; C07K 17/00; C12P 21/08; G01N 33/574; C12Q 1/68

IPC 8 full level

A61K 45/00 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 17/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

A61P 25/28 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); A61P 43/00 (2017.12); G01N 33/6872 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 9961459A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9961459 A1 19991202; AU 3988399 A 19991213; CA 2329506 A1 19991202; EP 1082334 A1 20010314; JP 2002516335 A 20020604

DOCDB simple family (application)

US 9910581 W 19990513; AU 3988399 A 19990513; CA 2329506 A 19990513; EP 99923016 A 19990513; JP 2000550863 A 19990513