Global Patent Index - EP 1082339 A2

EP 1082339 A2 2001-03-14 - RATIONALLY DESIGNED PEPTIDES, PRODUCTION AND USE THEREOF

Title (en)

RATIONALLY DESIGNED PEPTIDES, PRODUCTION AND USE THEREOF

Title (de)

RATIONAL DESIGNTE PEPTIDE, IHRE HERSTELLUNG UND IHRE VERWENDUNG

Title (fr)

PEPTIDES CON US DE MANIERE RATIONNELLE, LEUR PRODUCTION ET LEUR UTILISATION

Publication

EP 1082339 A2 (DE)

Application

EP 99936345 A

Priority

  • DE 9901575 W
  • DE 19824641 A
  • DE 19826442 A

Abstract (en)

[origin: WO9962933A2] The invention relates to rationally designed peptides and to the production and use thereof for biotechnological, medical, diagnostic and therapeutic purposes. The method for generating peptides that are suitable for bonding auto-antibodies is characterized by the following: identification of a seed peptide with the suitable activity, production of a small number of peptide variants from the physico-chemical area around the seed peptide using a computer-assisted calculation method; synthesis and testing of the activity of said peptide variants; modelling of a quantitative sequence/activity ratio by means of an artificial neuronal network; and the production of peptides by simulated evolution in the sequence area using the trained neuronal network. The invention specifically relates to the peptide DRFGDKIAF.

IPC 1-7 (main, further and additional classification)

C07K 1/00; A61K 38/04; C07B 61/00; C07K 1/04; C07K 7/06; C07K 14/705; C12N 15/10

IPC 8 full level (invention and additional information)

C07K 1/04 (2006.01); C07K 7/06 (2006.01)

CPC (invention and additional information)

C07K 7/06 (2013.01); C07K 1/047 (2013.01)

Citation (search report)

See references of WO 9962933A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9962933 A2 19991209; WO 9962933 A3 20000406; AU 5150499 A 19991220; EP 1082339 A2 20010314

INPADOC legal status


2002-03-27 [18W] WITHDRAWN

- Date of withdrawal: 20020130

2001-03-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001221

2001-03-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE