Global Patent Index - EP 1082419 A2

EP 1082419 A2 2001-03-14 - COMBINATION THERAPY USING NUCLEIC ACIDS AND CONVENTIONAL DRUGS

Title (en)

COMBINATION THERAPY USING NUCLEIC ACIDS AND CONVENTIONAL DRUGS

Title (de)

KOMBINATIONSTHERAPIE MIT NUCLEINSÄUREN UND KONVENTIONELLEN WIRKSTOFFE

Title (fr)

TRAITEMENT ASSOCIE UTILISANT DES ACIDES NUCLEIQUES ET DES MEDICAMENTS CLASSIQUES

Publication

EP 1082419 A2 (EN)

Application

EP 99917711 A

Priority

  • CA 9900371 W
  • US 8266598 P
  • US 11163598 P
  • US 29566399 A

Abstract (en)

[origin: WO9954445A2] The present invention relates to methods for increasing the efficiency of transformation of cycling cells, the methods comprising synchronizing cells at a first stage of the cell cycle, and transforming the cells at a second stage of the cell cycle within about one cell cycle of the first stage with a genetically engineered nucleic acid that encodes a desired gene product. The invention further relates to cancer therapy and, in particular, to methods of efficiently transforming cancer cells with nucleic acids that encode gene products that inhibit the growth of cancer cells.

IPC 1-7 (main, further and additional classification)

C12N 15/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 41/00 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C12N 5/10 (2006.01); C12N 15/87 (2006.01)

CPC (invention and additional information)

A61K 48/00 (2013.01); A61K 41/0038 (2013.01); C12N 15/87 (2013.01)

Citation (search report)

See references of WO 9954445A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9954445 A2 19991028; WO 9954445 A3 19991209; AU 3591299 A 19991108; AU 762986 B2 20030710; CA 2325561 A1 19991028; EP 1082419 A2 20010314; JP 2002512258 A 20020423

INPADOC legal status


2006-07-12 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060114

2001-03-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001122

2001-03-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE