Global Patent Index - EP 1082443 A1

EP 1082443 A1 2001-03-14 - SERINE PROTEASE VARIANTS HAVING AMINO ACID DELETIONS AND SUBSTITUTIONS

Title (en)

SERINE PROTEASE VARIANTS HAVING AMINO ACID DELETIONS AND SUBSTITUTIONS

Title (de)

SERINPROTEASEVARIANTEN MIT DELETIERTEN UND SUBSTITUIERTEN AMINOSÄUREN

Title (fr)

VARIANTS DE SERINE-PROTEASES AYANT DES DELETIONS ET DES SUBSTITUTIONS D'ACIDES AMINES

Publication

EP 1082443 A1 (EN)

Application

EP 99907806 A

Priority

  • IB 9900520 W
  • US 7947798 P

Abstract (en)

[origin: WO9949057A1] The present invention relates to variants of serine proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates to variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a deletion and, optionally, a substitution of one or more specifically identified positions corresponding to subtilisin BPN'. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants.

IPC 1-7 (main, further and additional classification)

C12N 15/57; A61K 7/00; C12N 9/54

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 8/00 (2006.01); A61K 8/02 (2006.01); A61K 8/66 (2006.01); A61K 8/96 (2006.01); A61Q 5/02 (2006.01); A61Q 11/00 (2006.01); A61Q 19/00 (2006.01); A61Q 19/10 (2006.01); C12N 9/54 (2006.01); C12N 15/57 (2006.01); A61Q 5/00 (2006.01)

CPC (invention and additional information)

C12N 9/54 (2013.01); A61K 8/0208 (2013.01); A61K 8/66 (2013.01); A61Q 19/00 (2013.01); A61K 2800/86 (2013.01); A61Q 5/00 (2013.01); A61Q 11/00 (2013.01); A61Q 19/10 (2013.01)

Citation (search report)

See references of WO 9949057A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9949057 A1 19990930; AR 023021 A1 20020904; AU 2742699 A 19991018; AU 750336 B2 20020718; BR 9909147 A 20001205; CA 2324422 A1 19990930; CN 1303437 A 20010711; EP 1082443 A1 20010314; JP 2002518993 A 20020702

INPADOC legal status


2005-07-20 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050104

2004-06-09 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040422

2001-03-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001227

2001-03-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE