EP 1082443 A1 20010314 - SERINE PROTEASE VARIANTS HAVING AMINO ACID DELETIONS AND SUBSTITUTIONS
Title (en)
SERINE PROTEASE VARIANTS HAVING AMINO ACID DELETIONS AND SUBSTITUTIONS
Title (de)
SERINPROTEASEVARIANTEN MIT DELETIERTEN UND SUBSTITUIERTEN AMINOSÄUREN
Title (fr)
VARIANTS DE SERINE-PROTEASES AYANT DES DELETIONS ET DES SUBSTITUTIONS D'ACIDES AMINES
Publication
Application
Priority
- IB 9900520 W 19990325
- US 7947798 P 19980326
Abstract (en)
[origin: WO9949057A1] The present invention relates to variants of serine proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates to variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a deletion and, optionally, a substitution of one or more specifically identified positions corresponding to subtilisin BPN'. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants.
IPC 1-7
IPC 8 full level
A61K 8/00 (2006.01); A61K 8/02 (2006.01); A61K 8/66 (2006.01); A61K 8/96 (2006.01); A61Q 5/02 (2006.01); A61Q 11/00 (2006.01); A61Q 19/00 (2006.01); A61Q 19/10 (2006.01); C12N 9/54 (2006.01); C12N 15/09 (2006.01); C12N 15/57 (2006.01); A61Q 5/00 (2006.01)
CPC (source: EP KR)
A61K 8/0208 (2013.01 - EP); A61K 8/66 (2013.01 - EP); A61Q 19/00 (2013.01 - EP); C12N 9/50 (2013.01 - KR); C12N 9/54 (2013.01 - EP); A61K 2800/86 (2013.01 - EP); A61Q 5/00 (2013.01 - EP); A61Q 11/00 (2013.01 - EP); A61Q 19/10 (2013.01 - EP)
Citation (search report)
See references of WO 9949057A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9949057 A1 19990930; AR 023021 A1 20020904; AU 2742699 A 19991018; AU 750336 B2 20020718; BR 9909147 A 20001205; CA 2324422 A1 19990930; CN 1303437 A 20010711; EP 1082443 A1 20010314; JP 2002518993 A 20020702; KR 20010052223 A 20010625
DOCDB simple family (application)
IB 9900520 W 19990325; AR P990101373 A 19990326; AU 2742699 A 19990325; BR 9909147 A 19990325; CA 2324422 A 19990325; CN 99806571 A 19990325; EP 99907806 A 19990325; JP 2000538017 A 19990325; KR 20007010692 A 20000926