EP 1082445 A2 20010314 - ADENO-ASSOCIATED VIRAL VECTOR-MEDIATED EXPRESSION OF FACTOR VIII ACTIVITY
Title (en)
ADENO-ASSOCIATED VIRAL VECTOR-MEDIATED EXPRESSION OF FACTOR VIII ACTIVITY
Title (de)
EXPRESSION VON FAKTOR VIII DURCH AUF ADENO-ASSOZIIERTEN VIREN BASIERENDEN VEKTOREN
Title (fr)
EXPRESSION DE L'ACTIVITE DU FACTEUR VIII PAR UN VECTEUR VIRAL ADENO-ASSOCIE
Publication
Application
Priority
- US 9910472 W 19990527
- US 8442398 A 19980527
Abstract (en)
[origin: WO9961595A2] The instant invention provides methods and materials for expressing polypeptides with factor VIII activity comprising administering at least two rAAV vectors encoding different domains of human factor VIII and at least the heavy and light chains.
IPC 1-7
IPC 8 full level
A61K 35/76 (2006.01); A61K 38/43 (2006.01); A61K 48/00 (2006.01); A61P 7/04 (2006.01); C07K 14/755 (2006.01); C12N 15/09 (2006.01); C12N 15/864 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); A61P 7/04 (2017.12); C07K 14/755 (2013.01); C12N 15/86 (2013.01); C12N 2750/14143 (2013.01)
Citation (search report)
See references of WO 9961595A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9961595 A2 19991202; WO 9961595 A3 20000127; AU 4185699 A 19991213; CA 2329143 A1 19991202; EP 1082445 A2 20010314; JP 2002516345 A 20020604
DOCDB simple family (application)
US 9910472 W 19990527; AU 4185699 A 19990527; CA 2329143 A 19990527; EP 99925606 A 19990527; JP 2000550980 A 19990527